Area of research
Cancer Research · Oncology
Research interest
Research interests include Cancer Genomics and Diagnostics, Cancer Immunotherapy and Biomarkers, Metabolomics and Mass Spectrometry Studies, and Cancer, Lipids, and Metabolism.
Diagnostic whole transcriptome sequencing in a series of 1233 FFPE solid tumor samples
Implementing whole genome and transcriptome sequencing for cancer patients in routine healthcare: a comprehensive guide to costing
EGFR-mediated local invasiveness and response to Cetuximab in head and neck cancer
Multi-omics analysis to uncover the molecular basis of tumor budding in head and neck squamous cell carcinoma
An immune responsive tumor microenvironment imprints into PBMCs and predicts outcome in advanced pancreatic cancer: lessons from the PREDICT trial
Advancing Lung Cancer Staging: Integrating IASLC Recommendations and Bioinformatics to Delineate Tumor Origins
Contribution of genetics to hematopoietic stem cell mobilization: a genomewide association study of 564 healthy donors mobilized with granulocyte colony-stimulating factor
Comprehensive genomic profiling requires a blended ecosystem of learning healthcare and clinical trials
1980P Tumor mutational burden (TMB) and proliferation as negative prognostic factors for ALK+ lung cancer: First results from the randomized ABP phase II trial
Tumour mutational burden: clinical utility, challenges and emerging improvements
High Concordance of Different Assays in the Determination of Homologous Recombination Deficiency–Associated Genomic Instability in Ovarian Cancer
Dissecting AI-based mutation prediction in lung adenocarcinoma: A comprehensive real-world study
An Analysis of <i>PIK3CA</i> Hotspot Mutations and Response to Neoadjuvant Therapy in Patients with Breast Cancer from Four Prospective Clinical Trials
Clinical Implementation of a High-Throughput Automated Comprehensive Genomic Profiling Test
Leveraging Off-Target Reads in Panel Sequencing for Homologous Recombination Repair Deficiency Screening in Tumor
The German Network for Personalized Medicine to enhance patient care and translational research
Multicentric pilot study to standardize clinical whole exome sequencing (WES) for cancer patients
Tumour budding-based grading as independent prognostic biomarker in HPV-positive and HPV-negative head and neck cancer
Real‐world data for precision cancer medicine—A European perspective
Accurate tumor purity determination is critical for the analysis of homologous recombination deficiency (HRD)
Homogenous TP53mut-associated tumor biology across mutation and cancer types revealed by transcriptome analysis
Spatial profiling of the microenvironment reveals low intratumoral heterogeneity and STK11-associated immune evasion in therapy-naïve lung adenocarcinomas
Data from Inferred Immune-Cell Activity Is an Independent Predictor of HER2-Negative Breast Cancer Prognosis and Response to Paclitaxel-Based Therapy in the GeparSepto Trial
Pan-cancer analysis of genomic scar patterns caused by homologous repair deficiency (HRD)
Genomic architecture of FGFR2 fusions in cholangiocarcinoma and its implication for molecular testing
<scp>Homologous recombination deficiency</scp> is inversely correlated with <scp>microsatellite instability</scp> and identifies immunologically cold tumors in most cancer types
The impact of TP53 co-mutations and immunologic microenvironment on outcome of lung cancer with EGFR exon 20 insertions
The journey of tumor-infiltrating lymphocytes as a biomarker in breast cancer: clinical utility in an era of checkpoint inhibition
Aligning tumor mutational burden (TMB) quantification across diagnostic platforms: phase II of the Friends of Cancer Research TMB Harmonization Project
Artificial intelligence and pathology: From principles to practice and future applications in histomorphology and molecular profiling