Area of research
Genetics · Reproductive Medicine
Research interest
Research interests include BRCA gene mutations in cancer, Ovarian cancer diagnosis and treatment, Testicular diseases and treatments, and CRISPR and Genetic Engineering.
Childhood, adolescent, and young adulthood cancer risk in <i>BRCA1</i> or <i>BRCA2</i> pathogenic variant carriers
Large-scale genome-wide association study of 398,238 women unveils seven novel loci associated with high-grade serous epithelial ovarian cancer risk
Genome-wide Association Study of Bladder Cancer Reveals New Biological and Translational Insights
Polygenic risk modeling for prediction of epithelial ovarian cancer risk
Copy number variants as modifiers of breast cancer risk for BRCA1/BRCA2 pathogenic variant carriers
Correction: Polygenic risk modeling for prediction of epithelial ovarian cancer risk
Identification of 22 susceptibility loci associated with testicular germ cell tumors
Breast and Prostate Cancer Risks for Male<i>BRCA1</i>and<i>BRCA2</i>Pathogenic Variant Carriers Using Polygenic Risk Scores
Risks of breast and ovarian cancer for women harboring pathogenic missense variants in BRCA1 and BRCA2 compared with those harboring protein truncating variants
Histological Features of Sporadic and Familial Testicular Germ Cell Tumors Compared and Analysis of Age-Related Changes of Histology
Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses
Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers
Transcriptome‐wide association study of breast cancer risk by estrogen‐receptor status
Polygenic Risk Modelling for Prediction of Epithelial Ovarian Cancer Risk
Association of Genomic Domains in <i>BRCA1</i> and <i>BRCA2</i> with Prostate Cancer Risk and Aggressiveness
Genome-wide association study identifies 32 novel breast cancer susceptibility loci from overall and subtype-specific analyses
<i>BRCA1</i>and<i>BRCA2</i>pathogenic sequence variants in women of African origin or ancestry
Assessment of Polygenic Architecture and Risk Prediction based on Common Variants Across Fourteen Cancers
Mendelian randomisation study of height and body mass index as modifiers of ovarian cancer risk in 22,588 BRCA1 and BRCA2 mutation carriers
A Transcriptome-Wide Association Study Among 97,898 Women to Identify Candidate Susceptibility Genes for Epithelial Ovarian Cancer Risk
Early Detection of Ovarian Cancer using the Risk of Ovarian Cancer Algorithm with Frequent CA125 Testing in Women at Increased Familial Risk – Combined Results from Two Screening Trials
Meta-analysis of five genome-wide association studies identifies multiple new loci associated with testicular germ cell tumor
The BRCA1-Δ11q Alternative Splice Isoform Bypasses Germline Mutations and Promotes Therapeutic Resistance to PARP Inhibition and Cisplatin
Identification of four novel susceptibility loci for oestrogen receptor negative breast cancer
Male breast cancer in BRCA1 and BRCA2 mutation carriers: pathology data from the Consortium of Investigators of Modifiers of BRCA1/2
Identification of independent association signals and putative functional variants for breast cancer risk through fine-scale mapping of the 12p11 locus
Inheritance of deleterious mutations at both BRCA1 and BRCA2 in an international sample of 32,295 women
Bone loss after oophorectomy among high-risk women: an NRG oncology/gynecologic oncology group study
Association of breast cancer risk in BRCA1 and BRCA2 mutation carriers with genetic variants showing differential allelic expression: identification of a modifier of breast cancer risk at locus 11q22.3
Assessing Associations between the AURKA-HMMR-TPX2-TUBG1 Functional Module and Breast Cancer Risk in BRCA1/2 Mutation Carriers