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Jun Xu

University of Iowa · US
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Area of research
Physiology · Pulmonary and Respiratory Medicine
Research interest
Research focused on Primary sclerosing cholangitis and Farnesoid X receptor, with related work in Gene silencing, Bone marrow, Stem cell. Notable publications include 'The Nonsteroidal Farnesoid X Receptor Agonist Cilofexor (GS‐9674) Improves Markers of Cholestasis and Liver Injury in Patients With Primary Sclerosing Cholangitis', 'Atorvastatin-pretreated mesenchymal stem cell-derived extracellular vesicles promote cardiac repair after myocardial infarction via shifting macrophage polarization by targeting...', and 'Down-regulation of HIF-1α inhibits the proliferation, migration, and invasion of gastric cancer by inhibiting PI3K/AKT pathway and VEGF expression'.
h-index
citations
412
works
7
NIH funding
primary concept
email

Recent publications

Cilofexor in non-cirrhotic primary sclerosing cholangitis (PRIMIS): a randomised, double-blind, multicentre, placebo-controlled, phase 3 trial
˜The œLancet. Gastroenterology & hepatology 2025cited by 5position: middledoi
A meta-learning-based robust federated learning for diagnosing lung adenocarcinoma and tuberculosis granulomas
Frontiers in Oncology 2025cited by 1position: middledoi
Atorvastatin-pretreated mesenchymal stem cell-derived extracellular vesicles promote cardiac repair after myocardial infarction via shifting macrophage polarization by targeting microRNA-139-3p/Stat1 pathway
BMC Medicine 2023cited by 73position: middledoi
Hypoxic preconditioned aged BMSCs accelerates MI injury repair by modulating inflammation, oxidative stress and apoptosis
Biochemical and Biophysical Research Communications 2022cited by 10position: lastdoi
A Fibrosis‐Independent Hepatic Transcriptomic Signature Identifies Drivers of Disease Progression in Primary Sclerosing Cholangitis
Hepatology 2020cited by 24position: middledoi
The Nonsteroidal Farnesoid X Receptor Agonist Cilofexor (GS‐9674) Improves Markers of Cholestasis and Liver Injury in Patients With Primary Sclerosing Cholangitis
Hepatology 2019cited by 256position: middledoi
Down-regulation of HIF-1α inhibits the proliferation, migration, and invasion of gastric cancer by inhibiting PI3K/AKT pathway and VEGF expression
Bioscience Reports 2018cited by 51position: middledoi
Angelica Sinensis attenuates inflammatory reaction in experimental rat models having spinal cord injury.
PubMed 2015cited by 21position: first
Ex vivo-expanded bone marrow stem cells home to the liver and ameliorate functional recovery in a mouse model of acute hepatic injury
Hepatobiliary & pancreatic diseases international 2012cited by 32position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Kris V. Kowdley · Velocity Clinical Research (United States)2 papers (2019–2020)Robert P. Myers · Meta (United States)2 papers (2019–2020)Christopher L. Bowlus · Washington State University2 papers (2019–2020)Andrew N. Billin · Gilead Sciences (United States)2 papers (2019–2020)Andrew J. Muir · Duke University2 papers (2019–2020)Chuhan Chung · Komipharm International (South Korea)2 papers (2019–2020)Michael Trauner · Universitätsklinik für Neurologie2 papers (2019–2020) · 1 papers (2020–2020)Lei Liu · Jiangsu University1 papers (2025–2025)Yang Liu · Zhengzhou University1 papers (2022–2022)Qiong Li · Nanjing Medical University1 papers (2025–2025)Jingjing Zhang · Nanjing University of Chinese Medicine1 papers (2018–2018)Jie Zhang · Shenzhen Center for Disease Control and Prevention1 papers (2022–2022)Lili Zhang · Hackensack University Medical Center1 papers (2023–2023)Xuemei Fan · Hebei Medical University1 papers (2022–2022)Sheng He · China National Bamboo Research Center1 papers (2022–2022)Jin Chen · Fudan University1 papers (2023–2023)Xiaosong Li · Soochow University1 papers (2023–2023)Rui Guo · Nanjing University of Chinese Medicine1 papers (2022–2022)Wenjuan Yin · Shanxi Medical University1 papers (2022–2022)
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