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Michael Hudecek

Lighthouse Guild · DE
Area of research
Oncology · Immunology
Research interest
Research interests include CAR-T cell therapy research, Immune Cell Function and Interaction, Virus-based gene therapy research, and Viral Infectious Diseases and Gene Expression in Insects.
h-index
49
citations
13,272
works
258
NIH funding
primary concept
Chimeric antigen receptor
email

Recent publications

Boosting CAR T-cell efficacy by blocking proteasomal degradation of membrane antigens.
2026cited by 2position: contributordoi
Vitamin C Conditioning Generates Tumor-Targeting CAR T Cells with Superior Cytotoxicity and Fitness in a Posttransplant Lymphoproliferative Disorder Tumor Model.
2026cited by 0position: contributordoi
Balancing the efficacy and safety of chimeric antigen receptor T-cell therapy by affinity combination.
2026cited by 0position: contributordoi
Loss of GPRC5D enhances the proliferative capacity and competitive fitness of myeloma upon anti-GPRC5D immunotherapy.
2026cited by 0position: contributordoi
Multiomic and Longitudinal Dissection of Immune Dynamics Associated with Parkinsonism after Ciltacabtagene Autoleucel Therapy.
2026cited by 0position: contributordoi
ROR1 CAR T cells and lenvatinib cooperatively target anaplastic thyroid carcinoma
2026cited by 0position: contributordoi
Design specifications for biomedical virtual twins in engineered adoptive cellular immunotherapies
npj Digital Medicine 2025cited by 6position: middledoi
Next-generation T cell immunotherapies engineered with CRISPR base and prime editing: challenges and opportunities
Nature Reviews Clinical Oncology 2025cited by 5position: lastdoi
Plasmapheresis facilitates soluble BCMA clearance and contributes to reversing primary resistance to anti-BCMA immunotherapy in multiple myeloma.
2025cited by 3position: contributordoi
Autocrine signaling in hormonally active cancer induces antigen expression for immunotherapy
2025cited by 2position: contributordoi
Boosting immune cells to combat cancer using CRISPR engineering and large-scale in vivo testing.
2025cited by 1position: contributordoi
<scp>LMP2A</scp> ‐Targeting <scp>CAR</scp> ‐T Cells Equipped With Inducible <scp>IL</scp> ‐18 to Address <scp>EBV</scp> ‐Associated Malignancies
HLA 2025cited by 0position: middledoi
Fine tuning towards the next generation of engineered T cells.
2025cited by 0position: contributordoi
Patient-reported outcomes in patients with hematologic malignancies treated with CAR T-cell therapy in Europe.
2025cited by 0position: contributordoi
TCR activation impairs CAR-T cytotoxicity against separate target cells
2025cited by 0position: contributordoi
A novel CAR T cell blend targeting PDPN and GD2 to overcome glioblastoma heterogeneity
2025cited by 0position: contributordoi
Engineering of potent CAR NK cells using non-viral Sleeping Beauty transposition from minimalistic DNA vectors
Molecular Therapy 2024cited by 43position: middledoi
Trust in and Acceptance of Artificial Intelligence Applications in Medicine: Mixed Methods Study.
2024cited by 41position: contributordoi
CAR T-cell therapy in multiple myeloma: mission accomplished?
2024cited by 25position: contributordoi
Mutation-specific CAR T cells as precision therapy for IGLV3-21R110 expressing high-risk chronic lymphocytic leukemia
Nature Communications 2024cited by 14position: middledoi
BCMA CAR-T cells in multiple myeloma-ready for take-off?
2024cited by 12position: contributordoi
Mutation-specific CAR T cells as precision therapy for IGLV3-21<sup>R110</sup> expressing high-risk chronic lymphocytic leukemia.
2024cited by 12position: contributordoi
Novel strategies to assess cytokine release mediated by chimeric antigen receptor T cells based on the adverse outcome pathway concept.
2024cited by 9position: contributordoi
The Spectrum of CAR Cellular Effectors: Modes of Action in Anti-Tumor Immunity
Cancers 2024cited by 8position: middledoi
Current Non-Viral-Based Strategies to Manufacture CAR-T Cells.
2024cited by 7position: contributordoi
The Spectrum of CAR Cellular Effectors: Modes of Action in Anti-Tumor Immunity.
2024cited by 5position: contributordoi
TCR/CD3-based synthetic antigen receptors (TCC) convey superior antigen sensitivity combined with high fidelity of activation.
2024cited by 3position: contributordoi
Cellular Therapies for Multiple Myeloma: Engineering Hope.
2024cited by 1position: contributordoi
Teclistamab impairs detection of BCMA CAR-T cells.
2023cited by 4position: contributordoi
Impaired FADD/BID signaling mediates cross-resistance to immunotherapy in Multiple Myeloma.
2023cited by 3position: contributordoi

Grants

No grants ingested yet.

Frequent collaborators

· 38 papers (2019–2026)Hermann Einsele · Ovarian Cancer Research Alliance21 papers (2018–2026) · 15 papers (2019–2026)Thomas Nerreter · Klinikum Würzburg Mitte10 papers (2019–2026)Leo Rasche · Janssen (United States)7 papers (2020–2026)Martin Kortüm · Klinikum Bielefeld6 papers (2021–2026) · 6 papers (2021–2026) · 5 papers (2021–2024)Halvard Bönig · Goethe-Institute United Kingdom5 papers (2018–2021)Dirk H. Busch · Universität Bayern4 papers (2023–2026)Markus Sauer · University of Colorado Boulder4 papers (2021–2026)Johannes M. Waldschmidt · University Medical Center Freiburg3 papers (2025–2026)Hannes Stockinger · Institute of Immunology3 papers (2020–2024)Miriam Alb · University of Würzburg3 papers (2019–2024)Susana Minguet · University Hospital and Clinics3 papers (2023–2024) · 3 papers (2023–2025)Vasco Dos Reis Goncalves · Universitätsklinikum Würzburg3 papers (2020–2024)Lukas Scheller · Universitätsklinikum Würzburg3 papers (2023–2024) · 3 papers (2021–2026)Sebastian Kobold · Ludwig-Maximilians-Universität München3 papers (2023–2024)