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Lainie P. Martin

University of Pennsylvania · US
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Area of research
Reproductive Medicine · Oncology
Research interest
Research interests include Ovarian cancer diagnosis and treatment, PARP inhibition in cancer therapy, HER2/EGFR in Cancer Research, and CAR-T cell therapy research.
h-index
41
citations
7,405
works
280
NIH funding
primary concept
email

Recent publications

Patient-reported outcomes from the MIRASOL trial evaluating mirvetuximab soravtansine versus chemotherapy in patients with folate receptor α-positive, platinum-resistant ovarian cancer: a randomised, open-label, phase 3 trial
The Lancet Oncology 2025cited by 24position: middledoi
NCCN Guidelines® Insights: Ovarian Cancer/Fallopian Tube Cancer/Primary Peritoneal Cancer, Version 3.2024
Journal of the National Comprehensive Cancer Network 2024cited by 104position: middledoi
Phase 1b study of mirvetuximab soravtansine, a folate receptor alpha (FRα)–targeting antibody-drug conjugate, in combination with carboplatin and bevacizumab in patients with platinum-sensitive ovarian cancer
Gynecologic Oncology 2024cited by 31position: middledoi
Mirvetuximab Soravtansine in FRα-Positive, Platinum-Resistant Ovarian Cancer
New England Journal of Medicine 2023cited by 377position: middledoi
Luveltamab tazevibulin (STRO-002), an anti-folate receptor alpha (FolRα) antibody drug conjugate (ADC), safety and efficacy in a broad distribution of FolRα expression in patients with recurrent epithelial ovarian cancer (OC): Update of STRO-002-GM1 phase 1 dose expansion cohort.
Journal of Clinical Oncology 2023cited by 26position: middledoi
NCCN Guidelines® Insights: Ovarian Cancer, Version 3.2022
Journal of the National Comprehensive Cancer Network 2022cited by 393position: middledoi
Identification of Patients With Ovarian Cancer Experiencing the Highest Benefit From Bevacizumab in the First-Line Setting on the Basis of Their Tumor-Intrinsic Chemosensitivity (KELIM): The GOG-0218 Validation Study
Journal of Clinical Oncology 2022cited by 72position: middledoi
MIRASOL: A randomized, open-label, phase 3 study of mirvetuximab soravtansine vs. investigator’s choice of chemotherapy in advanced high-grade epithelial ovarian, primary peritoneal, or fallopian tube cancers with high folate-alpha (FRα) expression (297)
Gynecologic Oncology 2022cited by 5position: middledoi
Ovarian Cancer, Version 2.2020, NCCN Clinical Practice Guidelines in Oncology
Journal of the National Comprehensive Cancer Network 2021cited by 707position: middledoi
Combination ATR and PARP Inhibitor (CAPRI): A phase 2 study of ceralasertib plus olaparib in patients with recurrent, platinum-resistant epithelial ovarian cancer
Gynecologic Oncology 2021cited by 116position: middledoi
Phase Ib study of mirvetuximab soravtansine, a folate receptor alpha (FRα)-targeting antibody-drug conjugate (ADC), in combination with bevacizumab in patients with platinum-resistant ovarian cancer
Gynecologic Oncology 2020cited by 138position: middledoi
Is Targeting the Folate Receptor in Ovarian Cancer Coming of Age?
The Oncologist 2019cited by 41position: middledoi
Safety lead-in of the MEK inhibitor trametinib in combination with GSK2141795, an AKT inhibitor, in patients with recurrent endometrial cancer: An NRG Oncology/GOG study
Gynecologic Oncology 2019cited by 41position: middledoi
Alisertib in Combination With Weekly Paclitaxel in Patients With Advanced Breast Cancer or Recurrent Ovarian Cancer
JAMA Oncology 2018cited by 90position: middledoi
Phase I combination study of the PARP inhibitor veliparib plus carboplatin and gemcitabine in patients with advanced ovarian cancer and other solid malignancies
Gynecologic Oncology 2018cited by 72position: lastdoi
Mirvetuximab soravtansine, a folate receptor alpha (FRα)-targeting antibody-drug conjugate (ADC), with pembrolizumab in platinum-resistant ovarian cancer (PROC): Initial results of an expansion cohort from FORWARD II, a phase Ib study
Annals of Oncology 2018cited by 28position: middledoi
Phase II evaluation of dalantercept in the treatment of persistent or recurrent epithelial ovarian cancer: An NRG Oncology/Gynecologic Oncology Group study
Gynecologic Oncology 2018cited by 16position: middledoi
CT Perfusion as an Early Biomarker of Treatment Efficacy in Advanced Ovarian Cancer: An ACRIN and GOG Study
Clinical Cancer Research 2017cited by 23position: middledoi
Weekly vs. Every-3-Week Paclitaxel and Carboplatin for Ovarian Cancer
New England Journal of Medicine 2016cited by 365position: middledoi
Ovarian Cancer, Version 1.2016, NCCN Clinical Practice Guidelines in Oncology
Journal of the National Comprehensive Cancer Network 2016cited by 322position: middledoi
Uterine Neoplasms, Version 1.2014
Journal of the National Comprehensive Cancer Network 2014cited by 183position: middledoi
Ovarian Cancer, Version 2.2013
Journal of the National Comprehensive Cancer Network 2013cited by 130position: middledoi
Ovarian Cancer, Version 3.2012
Journal of the National Comprehensive Cancer Network 2012cited by 196position: middledoi
Phase II trial of nab-paclitaxel in the treatment of recurrent or persistent advanced cervix cancer: A gynecologic oncology group study
Gynecologic Oncology 2012cited by 70position: middledoi
Phase I trial of axitinib combined with platinum doublets in patients with advanced non-small cell lung cancer and other solid tumours
British Journal of Cancer 2012cited by 31position: middledoi
Phase I study of axitinib combined with paclitaxel, docetaxel or capecitabine in patients with advanced solid tumours
British Journal of Cancer 2012cited by 24position: firstdoi

Grants

No grants ingested yet.

Frequent collaborators

David M. O’Malley · Bexley Hall7 papers (2013–2024)Kathleen N. Moore · Oklahoma City University6 papers (2018–2024)Michael J. Birrer · University of Arkansas at Little Rock5 papers (2016–2020)Robert A. Burger · Mersana Therapeutics (United States)4 papers (2013–2022)Ursula A. Matulonis · Harvard University4 papers (2013–2024)Lucy Gilbert · McGill University Health Centre4 papers (2018–2024)Richard T. Penson · Harvard University3 papers (2013–2020)Robert L. Coleman · MD Anderson Cancer Center Madrid3 papers (2017–2022)Gina Mantia-Smaldone · University of Lausanne3 papers (2020–2024)Joan L. Walker · Cornell University3 papers (2016–2022)Ignace Vergote · KU Leuven3 papers (2018–2024)Heidi J. Gray · University of Technology Sydney3 papers (2013–2018)Cesar M. Castro · Harvard University3 papers (2018–2024)Deborah K. Armstrong · Florida State University2 papers (2013–2021)Roger B. Cohen · University of Pennsylvania2 papers (2012–2012)Russell J. Schilder · Thomas Jefferson University2 papers (2019–2023)Roy S. Herbst · Yale New Haven Hospital2 papers (2012–2012)Stephen C. Rubin · Roswell Park Comprehensive Cancer Center2 papers (2016–2017) · 2 papers (2012–2012)Thomas A. Samuel · Roswell Park Comprehensive Cancer Center2 papers (2012–2012)
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