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Xiaochun Li

Southwestern Medical Center · US
Area of research
Molecular Biology · Cell Biology
Research interest
Research interests include Cellular transport and secretion, Calcium signaling and nucleotide metabolism, Sphingolipid Metabolism and Signaling, and Hedgehog Signaling Pathway Studies.
h-index
49
citations
7,231
works
224
NIH funding
primary concept
email

Recent publications

Designed endocytosis-inducing proteins degrade targets and amplify signals
Nature 2024cited by 115position: middledoi
Urine multi-index intelligent detection based on polymer/paper hybrid microfluidic biochip for hyperuricemia monitoring
Analytica Chimica Acta 2024cited by 7position: lastdoi
<scp>GPR35</scp> and mediators from platelets and mast cells in neutrophil migration and inflammation
Immunological Reviews 2023cited by 42position: middledoi
Effect of TiC nano-treating on the fluidity and solidification behavior of aluminum alloy 6063
Journal of Materials Processing Technology 2023cited by 33position: lastdoi
Transmembrane protein CD69 acts as an S1PR1 agonist
eLife 2023cited by 32position: lastdoi
Structure of S1PR2–heterotrimeric G <sub>13</sub> signaling complex
Science Advances 2022cited by 48position: lastdoi
Molecular basis of cholesterol efflux via ABCG subfamily transporters
Proceedings of the National Academy of Sciences 2021cited by 80position: lastdoi
RUNX1-mutated families show phenotype heterogeneity and a somatic mutation profile unique to germline predisposed AML
Blood Advances 2020cited by 152position: middledoi
Pharmacodynamics of natalizumab extended interval dosing in MS
Neurology Neuroimmunology & Neuroinflammation 2020cited by 30position: middledoi
Focal Irradiation and Systemic TGFβ Blockade in Metastatic Breast Cancer
Clinical Cancer Research 2018cited by 247position: middledoi
Human TRPML1 channel structures in open and closed conformations
Nature 2017cited by 155position: lastdoi
3.3 Å structure of Niemann–Pick C1 protein reveals insights into the function of the C-terminal luminal domain in cholesterol transport
Proceedings of the National Academy of Sciences 2017cited by 100position: firstdoi
Clues to the mechanism of cholesterol transfer from the structure of NPC1 middle lumenal domain bound to NPC2
Proceedings of the National Academy of Sciences 2016cited by 184position: firstdoi
Structure of human Niemann–Pick C1 protein
Proceedings of the National Academy of Sciences 2016cited by 158position: firstdoi
Triazoles inhibit cholesterol export from lysosomes by binding to NPC1
Proceedings of the National Academy of Sciences 2016cited by 71position: middledoi
Phase II study of irinotecan in combination with bevacizumab in recurrent ovarian cancer
Gynecologic Oncology 2016cited by 31position: middledoi
The V-motifs facilitate the substrate capturing step of the PTS elevator mechanism
Journal of Structural Biology 2016cited by 4position: middledoi
Structure of an integral membrane sterol reductase from Methylomicrobium alcaliphilum
Nature 2014cited by 62position: firstdoi

Grants

Some problems in harmonic analysis
NSF2350101$327,4412024–2027PIRePORTER
Fundamental Study on Nanotechnology Enabled Arc Welding of High Strength Aluminum Alloys
NSF2230828$380,7072023–2025PIRePORTER
EAGER: Properties and Manufacturing of Transformative Aluminum Nanocomposite Electrical Conductors
NSF1639164$299,1232016–2018PIRePORTER
Collaborative Research: Nanoparticle-Enabled Mechanisms for Growth Control in Immiscible Alloys under Regular Cooling
NSF1562252$171,5192016–2019PIRePORTER
Laser Additive Manufacturing of Metal Matrix Nanocomposites
NSF1538694$301,8952015–2018PIRePORTER
Collaborative Research: Friction Stir Processing of Cast Metal Matrix Nanocomposites
NSF1463627$86,2162015–2018PIRePORTER
SNM: Thermal Drawing of Fibers with Individually Addressable Nanoelectrode Array for Cellular Electrophysiology
NSF1449395$1,287,4392014–2020PIRePORTER
Collaborative Research: Fundamental Study and Pragmatic Enhancement of Rock Cutting/Drilling for Oil Exploration through Embedded Thin Film Sensor Arrays in PCD Inserts
NSF1439351$74,8782014–2016PIRePORTER
Collaborative Research: Fundamental Study and Pragmatic Enhancement of Rock Cutting/Drilling for Oil Exploration through Embedded Thin Film Sensor Arrays in PCD Inserts
NSF1300188$125,0002013–2014PIRePORTER
Collaborative Research: Embedding of Thin Film Sensors in Advanced Ceramic Tools for Micro/Nano Scale Thermomechanical Measurements in and Near Tool-Workpiece Interface
NSF0824713$245,9132008–2011PIRePORTER
Problems in Harmonic Analysis
NSF0801154$161,5942008–2012PIRePORTER
Collaborative Research/GOALI - Ceramic Nanoparticle Reinforced Aluminum Matrix Composites: An Integrated Processing, Characterization and Modeling Approach
NSF0625847$125,7332006–2009PIRePORTER
Problems in Harmonic Analysis
NSF0630818$15,9022006–2007PIRePORTER
NIRT/GOALI: Fundamental Study of Bulk Magnesium Matrix Nanocomposites Fabricated by Ultrasonic Cavitation Based Solidification Processing
NSF0506767$1,100,0002005–2009PIRePORTER
SIRG/Collaborative Research: Distributed Subwavelength Micro Photonic Sensors for In-situ Monitoring with High Spatial and Temporal Resolution in Manufacturing Environments
NSF0529361$456,8282005–2008PIRePORTER
Problems in harmonic analysis
NSF0456976$117,8032005–2008PIRePORTER
Sensors and Sensor Networks: Design, Fabrication and Application of Distributed Micro Sensors Embedded in Metal Tooling
NSF0330356$590,0382003–2006PIRePORTER
CAREER: Laser-Assisted Layered Manufacturing of 3D Mesoscale Structures With Embedded Micro Sensors and Actuators
NSF0134583$381,0002002–2008PIRePORTER
Problems in Harmonic Analysis
NSF0140376$86,1012002–2006PIRePORTER

Frequent collaborators

Günter Blobel · Howard Hughes Medical Institute5 papers (2014–2017)Jiawei Wang · South China Agricultural University3 papers (2016–2017)Jason G. Cyster · Howard Hughes Medical Institute3 papers (2022–2023)Judith D. Goldberg · NYU Langone Health3 papers (2016–2020)Michael Trinh · The University of Texas Southwestern Medical Center2 papers (2016–2017)Hongwen Chen · Howard Hughes Medical Institute2 papers (2022–2023)Feiran Lu · The University of Texas Southwestern Medical Center2 papers (2016–2017)Philip Schmiege · The University of Texas Southwestern Medical Center2 papers (2017–2017)Jin Wang · Fudan University1 papers (2021–2021) · 1 papers (2016–2016)Hao Qi · Zhejiang University1 papers (2024–2024)Qing Xue · Shanxi Medical University1 papers (2024–2024)Qi Hao · Henan University1 papers (2016–2016)Piyali Saha · University of Chicago1 papers (2016–2016) · 1 papers (2018–2018)Marissa Chou · University of California, San Francisco1 papers (2023–2023)Akash Das · University of Calcutta1 papers (2016–2016)Carol Felix · University of California, Los Angeles1 papers (2018–2018)Leticia Esparza · The University of Texas Southwestern Medical Center1 papers (2021–2021)Qiren Liang · Southwestern Medical Center1 papers (2016–2016)