Matthias Klein

NIK-driven IL-23 production by myeloid cells is a key factor in the development of autoimmune inflammation.

Metabolic reprogramming of interleukin-17-producing γδ T cells promotes ACC1-mediated de novo lipogenesis under psoriatic conditions

Polyamines regulate adaptive antitumor immunity by functional specialization of regulatory T cells

Constitutive expression of the transcriptional co-activator IκBζ promotes melanoma growth and immunotherapy resistance

Unveiling IRF4-steered regulation of context-dependent effector programs in CD4+ T cells under Th17- and Treg-skewing conditions

Menin-inhibition boosts CAR-T cell therapy against NPM1 mutated and KMT2A-rearranged acute myeloid leukemia

Single‐Cell Hyperthermia: Diamond Quantum Thermometry Reveals Thermal Control of Macrophage Polarization

Role of CD5 signalling for pro-inflammatory Th17 response in multiple sclerosis

Single-cell chromatin landscape and DNA methylation patterns reveal shared molecular programs in human tumor and non-tumor tissue CCR8 ⁺ Treg cells

CSF1R and IL1R1 inhibitors synergistically attenuate the early pathogenesis of traumatic brain injury in mice

Data from IL18 Receptor Signaling Regulates Tumor-Reactive CD8<sup>+</sup> T-cell Exhaustion via Activation of the IL2/STAT5/mTOR Pathway in a Pancreatic Cancer Model

Supplementary Data from IL18 Receptor Signaling Regulates Tumor-Reactive CD8<sup>+</sup> T-cell Exhaustion via Activation of the IL2/STAT5/mTOR Pathway in a Pancreatic Cancer Model

Supplementary Data from IL18 Receptor Signaling Regulates Tumor-Reactive CD8<sup>+</sup> T-cell Exhaustion via Activation of the IL2/STAT5/mTOR Pathway in a Pancreatic Cancer Model

IL-17A-producing CD8 ⁺ T cells promote PDAC via induction of inflammatory cancer-associated fibroblasts

IL18 Receptor Signaling Regulates Tumor-Reactive CD8+ T-cell Exhaustion via Activation of the IL2/STAT5/mTOR Pathway in a Pancreatic Cancer Model

IL18 Receptor Signaling Regulates Tumor-Reactive CD8+ T-cell Exhaustion via Activation of the IL2/STAT5/mTOR Pathway in a Pancreatic Cancer Model.

A20 regulates lymphocyte adhesion in murine neuroinflammation by restricting endothelial ICOSL expression in the CNS

A20 regulates lymphocyte adhesion in murine neuroinflammation by restricting endothelial ICOSL expression in the CNS

Tumor-infiltrating CCR2+ inflammatory monocytes counteract specific immunotherapy

DKK3 Promotes Oxidative Stress‒Induced Fibroblast Activity

Modulation of cellular transcriptome and proteome composition by azidohomoalanine—implications on click chemistry–based secretome analysis

Data from IL18 Receptor Signaling Regulates Tumor-Reactive CD8<sup>+</sup> T-cell Exhaustion via Activation of the IL2/STAT5/mTOR Pathway in a Pancreatic Cancer Model

Supplementary Data from IL18 Receptor Signaling Regulates Tumor-Reactive CD8<sup>+</sup> T-cell Exhaustion via Activation of the IL2/STAT5/mTOR Pathway in a Pancreatic Cancer Model

Supplementary Data from IL18 Receptor Signaling Regulates Tumor-Reactive CD8<sup>+</sup> T-cell Exhaustion via Activation of the IL2/STAT5/mTOR Pathway in a Pancreatic Cancer Model

Supplementary Data from IL18 Receptor Signaling Regulates Tumor-Reactive CD8<sup>+</sup> T-cell Exhaustion via Activation of the IL2/STAT5/mTOR Pathway in a Pancreatic Cancer Model

Data from IL18 Receptor Signaling Regulates Tumor-Reactive CD8<sup>+</sup> T-cell Exhaustion via Activation of the IL2/STAT5/mTOR Pathway in a Pancreatic Cancer Model

Supplementary Data from IL18 Receptor Signaling Regulates Tumor-Reactive CD8<sup>+</sup> T-cell Exhaustion via Activation of the IL2/STAT5/mTOR Pathway in a Pancreatic Cancer Model

Proinflammatory CD20 ⁺ T cells contribute to CNS-directed autoimmunity

Early posttraumatic CSF1R inhibition via PLX3397 leads to time- and sex-dependent effects on inflammation and neuronal maintenance after traumatic brain injury in mice

Selected commensals educate the intestinal vascular and immune system for immunocompetence