Area of research
Hematology · Genetics
Research interest
Research interests include Blood Coagulation and Thrombosis Mechanisms, Hemophilia Treatment and Research, Platelet Disorders and Treatments, and Virus-based gene therapy research.
Dissection of pleiotropic effects of variants in and adjacent to F8 exon 19 and rescue of mRNA splicing and protein function
Clustered <i>F8</i> missense mutations cause hemophilia A by combined alteration of splicing and protein biosynthesis and activity
Expression of Human Tissue Factor Pathway Inhibitor on Vascular Smooth Muscle Cells Inhibits Secretion of Macrophage Migration Inhibitory Factor and Attenuates Atherosclerosis in ApoE <sup>−/−</sup> Mice
Hyperactive PiggyBac Transposons for Sustained and Robust Liver-targeted Gene Therapy
Therapeutic levels of FVIII following a single peripheral vein administration of rAAV vector encoding a novel human factor VIII variant