Area of research
Genetics · Cancer Research
Research interest
Research interests include Glioma Diagnosis and Treatment, Cancer, Hypoxia, and Metabolism, ATP Synthase and ATPases Research, and Neuroblastoma Research and Treatments.
Clinical Efficacy of ONC201 in H3K27M-Mutant Diffuse Midline Gliomas Is Driven by Disruption of Integrated Metabolic and Epigenetic Pathways
TIM-3 blockade in diffuse intrinsic pontine glioma models promotes tumor regression and antitumor immune memory
Common molecular features of H3K27M DMGs and PFA ependymomas map to hindbrain developmental pathways
GD2-CAR T cell therapy for H3K27M-mutated diffuse midline gliomas
The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location
BAF Complex Maintains Glioma Stem Cells in Pediatric H3K27M Glioma
Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas
Targeting fibroblast growth factor receptors to combat aggressive ependymoma
EPCO-06. AGE- AND REGION-SPECIFIC MULTI-OMIC CHARACTERIZATION OF H3-K27M MUTANT DIFFUSE MIDLINE GLIOMA
Single-Cell RNA-Seq Reveals Cellular Hierarchies and Impaired Developmental Trajectories in Pediatric Ependymoma
EPEN-21. IMPAIRED NEURONAL-GLIAL FATE SPECIFICATION IN PEDIATRIC EPENDYMOMA REVEALED BY SINGLE-CELL RNA-SEQ
EXTH-37. TARGETING EPIGENETIC VULNERABILITIES IDENTIFIED FROM A CRISPR SCREEN IN H3.3K27M DIPG
EPCO-26. PROJECT HOPE: “PEDIATRIC AND AYA <i>H</i>IGH-GRADE GLIOMA <i>O</i>MICS <i>P</i>ROJ<i>E</i>CT”- A LONGITUDINAL MOLECULAR LANDSCAPE OF HIGH-GRADE GLIOMAS RESOLVED AT SINGLE-CELL LEVEL
Comparative analysis of the diffusion kurtosis imaging and diffusion tensor imaging in grading gliomas, predicting tumour cell proliferation and IDH-1 gene mutation status
Development of diagnostic criteria and a prognostic score for hepatitis B virus-related acute-on-chronic liver failure
Mst1 and Mst2 Are Essential Regulators of Trophoblast Differentiation and Placenta Morphogenesis