Area of research
Molecular Biology · Cell Biology
Research interest
Research interests include Congenital heart defects research, Zebrafish Biomedical Research Applications, Developmental Biology and Gene Regulation, and Pancreatic function and diabetes.
Mechanisms linking cytoplasmic decay of translation-defective mRNA to transcriptional adaptation
Pathogenic proteotoxicity of cryptic splicing is alleviated by ubiquitination and ER-phagy
Antigen presentation plays positive roles in the regenerative response to cardiac injury in zebrafish
The heart is a resident tissue for hematopoietic stem and progenitor cells in zebrafish
Distinct mechanisms regulate ventricular and atrial chamber wall formation
Single-cell-resolved dynamics of chromatin architecture delineate cell and regulatory states in zebrafish embryos
Conserved and context-dependent roles for pdgfrb signaling during zebrafish vascular mural cell development
Notochord vacuoles absorb compressive bone growth during zebrafish spine formation
Genetic compensation triggered by mutant mRNA degradation
Coronary Revascularization During Heart Regeneration Is Regulated by Epicardial and Endocardial Cues and Forms a Scaffold for Cardiomyocyte Repopulation
Peri-arterial specification of vascular mural cells from naïve mesenchyme requires Notch signaling
A whole organism small molecule screen identifies novel regulators of pancreatic endocrine development
Loss of pyruvate kinase M2 limits growth and triggers innate immune signaling in endothelial cells
Distinct myocardial lineages break atrial symmetry during cardiogenesis in zebrafish
Cyclopropane Modification of Trehalose Dimycolate Drives Granuloma Angiogenesis and Mycobacterial Growth through Vegf Signaling
Zebrafish mutants and TEAD reporters reveal essential functions for Yap and Taz in posterior cardinal vein development
Characterization of zebrafish (Danio rerio) muscle ankyrin repeat proteins reveals their conserved response to endurance exercise
Little Fish, Big Data: Zebrafish as a Model for Cardiovascular and Metabolic Disease
Guidelines for morpholino use in zebrafish
Frameshift indels introduced by genome editing can lead to in-frame exon skipping
Opposite effects of Activin type 2 receptor ligands on cardiomyocyte proliferation during development and repair
Bone morphogenetic protein signaling governs biliary‐driven liver regeneration in zebrafish through tbx2b and id2a
Wnt/β‐catenin signaling controls intrahepatic biliary network formation in zebrafish by regulating notch activity
Loss-of-function genetic tools for animal models: cross-species and cross-platform differences
Yap reprograms glutamine metabolism to increase nucleotide biosynthesis and enable liver growth
Fast revascularization of the injured area is essential to support zebrafish heart regeneration
Cloche is a bHLH-PAS transcription factor that drives haemato-vascular specification
A mutation in the atrial-specific myosin light chain gene (MYL4) causes familial atrial fibrillation
TAEL: A zebrafish-optimized optogenetic gene expression system with fine spatial and temporal control
In Vivo Visualization of Cardiomyocyte Apicobasal Polarity Reveals Epithelial to Mesenchymal-like Transition during Cardiac Trabeculation