Area of research
Molecular Biology · Cellular and Molecular Neuroscience
Research interest
Research interests include Receptor Mechanisms and Signaling, Protein Kinase Regulation and GTPase Signaling, Axon Guidance and Neuronal Signaling, and Nitric Oxide and Endothelin Effects.
The reciprocal endothelium-adipose loop fuels cardiometabolic diseases.
International Union of Basic and Clinical Pharmacology xxx: Applying an objective evaluation to the status of Class A orphan G protein-coupled receptors
Insulin Resistance: An Update on Biochemical and Pathophysiological Mechanisms and Impact on Various Diseases
Endothelial IGFBP6 suppresses vascular inflammation and atherosclerosis
Endothelial insulin resistance induced by adrenomedullin mediates obesity-associated diabetes.
PIEZO1 mediates periostin+ myofibroblast activation and pulmonary fibrosis in mice
Endothelial MICU1 protects against vascular inflammation and atherosclerosis by inhibiting mitochondrial calcium uptake
Endothelial IGFBP6 suppresses vascular inflammation and atherosclerosis.
The Concise Guide to PHARMACOLOGY 2025/26: Ion channels.
The clinical antiprotozoal drug halofuginone promotes weight loss by elevating GDF15 and FGF21.
Orphan G protein-coupled receptor GPRC5B controls macrophage function by facilitating prostaglandin E receptor 2 signaling.
The Concise Guide to PHARMACOLOGY 2025/26: G protein-coupled receptors.
FFAR4-mediated IL-6 release from islet macrophages promotes insulin secretion and is compromised in type-2 diabetes.
Phosphorylation of endothelial histone H3.3 serine 31 by PKN1 links flow-induced signaling to proatherogenic gene expression.
Diet modulates the therapeutic effects of dimethyl fumarate mediated by the immunometabolic neutrophil receptor HCAR2.
Inclusion of ACKR5 in the systematic nomenclature of atypical chemokine receptors.
Butyrate receptor HCAR2/GPR109A controls imiquimod-induced psoriasis-like skin inflammation.
Nuclear eNOS Interacts With and <i>S</i>-Nitrosates ADAR1 to Modulate Type I Interferon Signaling and Endothelial Function.
The tumor suppressor FAT1 controls YAP/TAZ protein degradation and tumor cell proliferation through E3 ligase MIB2.
Adventitial Fibroblasts Release Interleukin 6 After Vascular Injury and Induce Smooth Muscle Cell Proliferation and Neointima Formation.
Orphan receptor GPR153 facilitates vascular damage responses by modulating cAMP levels, YAP/TAZ signaling, and NF-κB activation.
Author response: Diet modulates the therapeutic effects of dimethyl fumarate mediated by the immunometabolic neutrophil receptor HCAR2
Hydroxycarboxylic acid receptors in GtoPdb v.2025.3
Regulation of Insulin Secretion Through Long‐Chain Fatty Acid Receptors
SPMs exert anti-inflammatory and pro-resolving effects through positive allosteric modulation of the prostaglandin EP4 receptor.
Clinically used broad-spectrum antibiotics compromise inflammatory monocyte-dependent antibacterial defense in the lung
Clinically used broad-spectrum antibiotics compromise inflammatory monocyte-dependent antibacterial defense in the lung.
Loss of Smooth Muscle Tenascin-X Inhibits Vascular Remodeling Through Increased TGF-β Signaling
Loss of Smooth Muscle Tenascin-X Inhibits Vascular Remodeling Through Increased TGF-β Signaling.
Protein kinase N promotes cardiac fibrosis in heart failure by fibroblast-to-myofibroblast conversion.