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John W. Weisel

California University of Pennsylvania · US
Area of research
Pulmonary and Respiratory Medicine · Hematology
Research interest
Research interests include Blood properties and coagulation, Platelet Disorders and Treatments, Erythrocyte Function and Pathophysiology, and Cell Adhesion Molecules Research.
h-index
79
citations
22,255
works
441
NIH funding
primary concept
email

Recent publications

Early pregravid correction of hemostasis assessed by novel biomarkers improves the outcomes of pregnancies in women with bad obstetric history.
2026cited by 0position: contributordoi
The Mechanisms of Contractile Dysfunction Following Chronic Partial Platelet Activation in (Pro)Thrombotic Conditions
2026cited by 0position: contributordoi
Shapes and dimensions of blood clots affect the rate and extent of platelet-driven clot contraction and determine the outcomes of thrombosis
Journal of Thrombosis and Haemostasis 2026cited by 0position: contributordoi
Red blood cell aggregation within a blood clot causes platelet-independent clot shrinkage.
2025cited by 6position: contributordoi
Exploring the thrombus niche: lessons learned and potential therapeutic opportunities.
2025cited by 3position: contributordoi
Neutrophil Extracellular Traps Promote Platelet-Driven Contraction of Inflammatory Blood Clots via Local Generation of Endogenous Thrombin and Softening of the Fibrin Network.
2025cited by 1position: contributordoi
Arterial human blood flow can be stopped by cables of VWF and platelets without coagulation.
2025cited by 1position: contributordoi
Ubiquitous clot contraction blockers hit ubiquitin and more.
2025cited by 0position: contributordoi
Platelets and Blood Clot Contraction
Platelets in Thrombotic and Non-Thrombotic Disorders 2025cited by 0position: contributordoi
Shapes and Dimensions of Blood Clots Affect the Rate and Extent of Platelet-Driven Clot Contraction and Will Determine the Outcomes of Thrombosis
2025cited by 0position: contributordoi
Megakaryocyte-induced contraction of plasma clots: cellular mechanisms and structural mechanobiology.
2024cited by 9position: contributordoi
A novel technique to quantify the kinetics of blood clot contraction based on the expulsion of fluorescently labeled albumin into serum
Journal of Thrombosis and Haemostasis 2024cited by 6position: contributordoi
Hormone-induced thrombosis is mediated through non-canonical fibrin(ogen) aggregation and a novel estrogen target in zebrafish
2024cited by 4position: contributordoi
Blood clot contraction: Mechanisms, pathophysiology, and disease
Research and Practice in Thrombosis and Haemostasis 2023cited by 87position: contributordoi
Role of red blood cells in clinically relevant bleeding tendencies and complications
Journal of Thrombosis and Haemostasis 2023cited by 35position: contributordoi
Activation of Piezo1 channels in compressed red blood cells augments platelet-driven contraction of blood clots
Journal of Thrombosis and Haemostasis 2023cited by 30position: lastdoi
Activation of Piezo1 channels in compressed red blood cells augments platelet-driven contraction of blood clots
Journal of Thrombosis and Haemostasis 2023cited by 30position: contributordoi
Combined computational modeling and experimental study of the biomechanical mechanisms of platelet-driven contraction of fibrin clots.
2023cited by 6position: contributordoi
Improving clots in trauma.
2023cited by 0position: contributordoi
Chorography of blood proteins
Journal of Thrombosis and Haemostasis 2023cited by 0position: contributordoi
Extent of intravital contraction of arterial and venous thrombi and pulmonary emboli.
2022cited by 21position: contributordoi
Pathology of lung-specific thrombosis and inflammation in COVID-19.
2021cited by 39position: contributordoi
Visualizing thrombosis to improve thrombus resolution.
2021cited by 31position: contributordoi
Pathologically stiff erythrocytes impede contraction of blood clots.
2021cited by 24position: contributordoi
Cleavage of talin by calpain promotes platelet-mediated fibrin clot contraction.
2021cited by 12position: contributordoi
Pathologically stiff erythrocytes impede contraction of blood clots: Reply to comment.
2021cited by 0position: contributordoi
Quantitative Morphology of Cerebral Thrombi Related to Intravital Contraction and Clinical Features of Ischemic Stroke
Stroke 2020cited by 65position: contributordoi
Rupture of blood clots: Mechanics and pathophysiology.
2020cited by 62position: contributordoi
Molecular packing structure of fibrin fibers resolved by X-ray scattering and molecular modeling
Soft Matter 2020cited by 25position: middledoi
Molecular packing structure of fibrin fibers resolved by X-ray scattering and molecular modeling.
2020cited by 14position: contributordoi

Grants

Collaborative Research: Experimental and Theoretical Studies of the Biomechanics of Fibrin Polymer
NSF1505662$390,0002015–2019PIRePORTER

Frequent collaborators

· 28 papers (2020–2026)Rustem I. Litvinov · Sylvana Research26 papers (2017–2026) · 22 papers (2020–2026)Rafael R. Khismatullin · Kazan Federal University5 papers (2022–2026)Alina D. Peshkova · University of Pennsylvania5 papers (2022–2026)Shakhnoza M. Saliakhutdinova · Kazan Federal University4 papers (2022–2026)Oleg V. Kim · University of Pennsylvania4 papers (2021–2025)Karl Hawkins · Swansea University4 papers (2012–2020)P. R. Williams · Swansea University3 papers (2014–2020)Natalia G. Evtugina · Kazan Federal University3 papers (2022–2026)Alina I. Khabirova · Kazan Federal University3 papers (2023–2026)Valerie Tutwiler · Springer Nature3 papers (2020–2021)Phillip Evans · Swansea University3 papers (2012–2015)Irina N. Chernysh · California University of Pennsylvania3 papers (2012–2017)Matthew Lawrence · Swansea University3 papers (2012–2015)M. Rowan Brown · Swansea University3 papers (2014–2020)Ahmed Sabra · Neurological Surgery2 papers (2014–2015)Wilbur A. Lam · Georgia Institute of Technology2 papers (2021–2021)Prashant K. Purohit · Philadelphia Fire Department2 papers (2020–2025)Don L. Siegel · Abramson Cancer Center2 papers (2021–2021)