Area of research
Genetics · Molecular Biology
Research interest
Research interests include Genetic Associations and Epidemiology, Bioinformatics and Genomic Networks, Treatment of Major Depression, and Health, Environment, Cognitive Aging.
Antidepressant Switching as a Proxy Phenotype for Drug Nonresponse: Investigating Clinical, Demographic, and Genetic Characteristics
Evaluation of polygenic scoring methods in five biobanks shows larger variation between biobanks than methods and finds benefits of ensemble learning
The GenoPred pipeline: a comprehensive and scalable pipeline for polygenic scoring
Integrating human endogenous retroviruses into transcriptome-wide association studies highlights novel risk factors for major psychiatric conditions
Metabolic activity of CYP2C19 and CYP2D6 on antidepressant response from 13 clinical studies using genotype imputation: a meta-analysis
A tool for translating polygenic scores onto the absolute scale using summary statistics
Evaluation of polygenic prediction methodology within a reference-standardized framework
Identifying the Common Genetic Basis of Antidepressant Response
Multiple measures of depression to enhance validity of major depressive disorder in the UK Biobank
Transcriptome-wide association study of treatment-resistant depression and depression subtypes for drug repurposing
Delineating the Genetic Component of Gene Expression in Major Depression
Impute.me: An Open-Source, Non-profit Tool for Using Data From Direct-to-Consumer Genetic Testing to Calculate and Interpret Polygenic Risk Scores
Cis-effects on gene expression in the human prenatal brain associated with genetic risk for neuropsychiatric disorders
Novel Insight Into the Etiology of Autism Spectrum Disorder Gained by Integrating Expression Data With Genome-wide Association Statistics
A transcriptome-wide association study implicates specific pre- and post-synaptic abnormalities in schizophrenia
Genome‐wide analysis of adolescent psychotic‐like experiences shows genetic overlap with psychiatric disorders
Are your covariates under control? How normalization can re-introduce covariate effects
Transcriptome analysis of genes and gene networks involved in aggressive behavior in mouse and zebrafish
Highly polygenic architecture of antidepressant treatment response: Comparative analysis of SSRI and NRI treatment in an animal model of depression
Comparative mRNA analysis of behavioral and genetic mouse models of aggression
Identification of genes and gene pathways associated with major depressive disorder by integrative brain analysis of rat and human prefrontal cortex transcriptomes
Genes and Gene Networks Implicated in Aggression Related Behaviour