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Stephen Opat

Monash Health · AU
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Area of research
Pathology and Forensic Medicine · Genetics
Research interest
Research interests include Lymphoma Diagnosis and Treatment, Chronic Lymphocytic Leukemia Research, Chronic Myeloid Leukemia Treatments, and Acute Lymphoblastic Leukemia research.
h-index
40
citations
11,138
works
358
NIH funding
primary concept
Medicine
email

Recent publications

Zanubrutinib Versus Bendamustine and Rituximab in Patients With Treatment-Naïve Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma: Median 5-Year Follow-Up of SEQUOIA
Journal of Clinical Oncology 2024cited by 49position: middledoi
Biomarker analysis of the ASPEN study comparing zanubrutinib with ibrutinib for patients with Waldenström macroglobulinemia
Blood Advances 2024cited by 31position: middledoi
International Prognostic Score for Nodular Lymphocyte–Predominant Hodgkin Lymphoma
Journal of Clinical Oncology 2024cited by 17position: middledoi
Sonrotoclax and Zanubrutinib as Frontline Treatment for CLL Demonstrates High MRD Clearance Rates with Good Tolerability: Data from an Ongoing Phase 1/1b Study BGB-11417-101
Blood 2024cited by 15position: middledoi
Zanubrutinib Versus Ibrutinib in Symptomatic Waldenström Macroglobulinemia: Final Analysis From the Randomized Phase III ASPEN Study
Journal of Clinical Oncology 2023cited by 100position: middledoi
Safety and efficacy of zanubrutinib in relapsed/refractory marginal zone lymphoma: final analysis of the MAGNOLIA study
Blood Advances 2023cited by 33position: firstdoi
Combination Treatment with Sonrotoclax (BGB-11417), a Second-Generation BCL2 Inhibitor, and Zanubrutinib, a Bruton Tyrosine Kinase (BTK) Inhibitor, Is Well Tolerated and Achieves Deep Responses in Patients with Treatment-Naïve Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (TN-CLL/SLL): Data from an Ongoing Phase 1/2 Study
Blood 2023cited by 23position: middledoi
ZANUBRUTINIB (ZANU) VERSUS BENDAMUSTINE + RITUXIMAB (BR) IN PATIENTS (PTS) WITH TREATMENT‐NAïVE (TN) CLL/SLL: EXTENDED FOLLOW‐UP OF THE SEQUOIA STUDY
Hematological Oncology 2023cited by 13position: middledoi
Polatuzumab vedotin plus bendamustine and rituximab or obinutuzumab in relapsed/refractory follicular lymphoma: a phase Ib/II study
Haematologica 2023cited by 10position: middledoi
Zanubrutinib versus bendamustine and rituximab in untreated chronic lymphocytic leukaemia and small lymphocytic lymphoma (SEQUOIA): a randomised, controlled, phase 3 trial
The Lancet Oncology 2022cited by 268position: middledoi
Fixed-duration ibrutinib plus venetoclax for first-line treatment of CLL: primary analysis of the CAPTIVATE FD cohort
Blood 2022cited by 233position: middledoi
Integrated clinical and genomic evaluation of guadecitabine (SGI-110) in peripheral T-cell lymphoma
Leukemia 2022cited by 28position: middledoi
Ibrutinib Plus Venetoclax for First-Line Treatment of Chronic Lymphocytic Leukemia: Primary Analysis Results From the Minimal Residual Disease Cohort of the Randomized Phase II CAPTIVATE Study
Journal of Clinical Oncology 2021cited by 227position: middledoi
Polatuzumab vedotin plus bendamustine and rituximab in relapsed/refractory DLBCL: survival update and new extension cohort data
Blood Advances 2021cited by 175position: middledoi
Zanubrutinib for the treatment of relapsed or refractory mantle cell lymphoma
Blood Advances 2021cited by 98position: middledoi
Pooled safety analysis of zanubrutinib monotherapy in patients with B-cell malignancies
Blood Advances 2021cited by 84position: middledoi
Clinical pharmacology and PK/PD translation of the second-generation Bruton’s tyrosine kinase inhibitor, zanubrutinib
Expert Review of Clinical Pharmacology 2021cited by 62position: lastdoi
SEQUOIA: Results of a Phase 3 Randomized Study of Zanubrutinib versus Bendamustine + Rituximab (BR) in Patients with Treatment-Naïve (TN) Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)
Blood 2021cited by 31position: middledoi
Fixed-duration (FD) first-line treatment (tx) with ibrutinib (I) plus venetoclax (V) for chronic lymphocytic leukemia (CLL)/small lymphocytic lymphoma (SLL): Primary analysis of the FD cohort of the phase 2 captivate study.
Journal of Clinical Oncology 2021cited by 23position: middledoi
Tazemetostat for patients with relapsed or refractory follicular lymphoma: an open-label, single-arm, multicentre, phase 2 trial
The Lancet Oncology 2020cited by 580position: middledoi
A randomized phase 3 trial of zanubrutinib vs ibrutinib in symptomatic Waldenström macroglobulinemia: the ASPEN study
Blood 2020cited by 446position: middledoi
Venetoclax plus obinutuzumab versus chlorambucil plus obinutuzumab for previously untreated chronic lymphocytic leukaemia (CLL14): follow-up results from a multicentre, open-label, randomised, phase 3 trial
The Lancet Oncology 2020cited by 325position: middledoi
Zanubrutinib for the treatment of patients with Waldenström macroglobulinemia: 3 years of follow-up
Blood 2020cited by 107position: middledoi
Zanubrutinib monotherapy for patients with treatment-naïve chronic lymphocytic leukemia and 17p deletion
Haematologica 2020cited by 102position: middledoi
Zanubrutinib for the treatment of MYD88 wild-type Waldenström macroglobulinemia: a substudy of the phase 3 ASPEN trial
Blood Advances 2020cited by 77position: middledoi
Ibrutinib (Ibr) Plus Venetoclax (Ven) for First-Line Treatment of Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL): 1-Year Disease-Free Survival (DFS) Results From the MRD Cohort of the Phase 2 CAPTIVATE Study
Blood 2020cited by 41position: middledoi
Efficacy and Safety of Zanubrutinib in Patients with Treatment-Naïve (TN) Chronic Lymphocytic Leukemia (CLL) or Small Lymphocytic Lymphoma (SLL) with del(17p): Follow-up Results from Arm C of the SEQUOIA (BGB-3111-304) Trial
Blood 2020cited by 36position: middledoi
Venetoclax and Obinutuzumab in Patients with CLL and Coexisting Conditions
New England Journal of Medicine 2019cited by 841position: middledoi
Phase 1 study of the selective BTK inhibitor zanubrutinib in B-cell malignancies and safety and efficacy evaluation in CLL
Blood 2019cited by 366position: middledoi
Ibrutinib (Ibr) Plus Venetoclax (Ven) for First-Line Treatment of Chronic Lymphocytic Leukemia (CLL)/Small Lymphocytic Lymphoma (SLL): Results from the MRD Cohort of the Phase 2 CAPTIVATE Study
Blood 2019cited by 41position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Constantine S. Tam · Alfred University12 papers (2019–2024)Alessandra Tedeschi · Centro de Investigación Biomédica en Red de Cáncer7 papers (2019–2022)Paolo Ghia · Vita-Salute San Raffaele University7 papers (2019–2024)Thomas J. Kipps · Moores Cancer Center6 papers (2015–2022)Tanya Siddiqi · City Of Hope National Medical Center5 papers (2019–2022)John N. Allan · Cornell University5 papers (2019–2022)Cathy Zhou · AbbVie (United States)5 papers (2019–2022)Joi Ninomoto · Pharmacyclics (United States)5 papers (2019–2022)Judith Trotman · Repatriation General Hospital5 papers (2019–2021)William G. Wierda · The University of Texas MD Anderson Cancer Center5 papers (2019–2022)Jane Huang · Los Angeles Medical Center4 papers (2019–2021)James P. Dean · CTI BioPharma (Italy)4 papers (2020–2022)Gavin Cull · Sir Charles Gairdner Hospital4 papers (2019–2021)Bryone J. Kuss · Flinders University4 papers (2019–2022)Edith Szafer‐Glusman · AbbVie (United States)4 papers (2020–2022)Ryan Jacobs · Levine Cancer Institute4 papers (2019–2021)David Simpson · The University of Melbourne4 papers (2019–2023)Carol Moreno · Universitat Autònoma de Barcelona4 papers (2020–2022)Sharon Jackson · University of Leeds4 papers (2020–2022)Javier Muñoz · Creighton University3 papers (2019–2021)
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