Area of research
Neurology · Molecular Biology
Research interest
Research focused on Autophagy and Cell biology, with related work in Disease, Oxidative stress, Programmed cell death. Notable publications include 'NRF2 controls iron homeostasis and ferroptosis through HERC2 and VAMP8', 'Breakdown of an Ironclad Defense System: The Critical Role of NRF2 in Mediating Ferroptosis', and 'NRF2 and Diabetes: The Good, the Bad, and the Complex'.
eNAMPT Is a Novel DAMP and Therapeutic Target in Human and Murine Pulmonary Fibrosis
Nonlipogenic ABCA1 Inducers (NLAI) for Alzheimer’s Disease Validated in a Mouse Model Expressing Human <i>APOE3/APOE4</i>
NRF2 controls iron homeostasis and ferroptosis through HERC2 and VAMP8
The NRF2-p97-NRF2 negative feedback loop
NRF2 and Diabetes: The Good, the Bad, and the Complex
Decreased autophagosome biogenesis, reduced NRF2, and enhanced ferroptotic cell death are underlying molecular mechanisms of non-alcoholic fatty liver disease
α-Syn overexpression, NRF2 suppression, and enhanced ferroptosis create a vicious cycle of neuronal loss in Parkinson's disease
Discovery and Development of a Selective Inhibitor of the ER Resident Chaperone Grp78
NRF2 Loss Accentuates Parkinsonian Pathology and Behavioral Dysfunction in Human α-Synuclein Overexpressing Mice
An NRF2 Perspective on Stem Cells and Ageing
MGST1, a new soldier of NRF2 in the battle against ferroptotic death
Enhanced NRF2 expression mitigates the decline in neural stem cell function during aging
Breakdown of an Ironclad Defense System: The Critical Role of NRF2 in Mediating Ferroptosis
Parkinson's Disease Skin Fibroblasts Display Signature Alterations in Growth, Redox Homeostasis, Mitochondrial Function, and Autophagy
A Role for Nrf2 Expression in Defining the Aging of Hippocampal Neural Stem Cells
Overexpression of alpha-synuclein at non-toxic levels increases dopaminergic cell death induced by copper exposure via modulation of protein degradation pathways