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Helen Gogas

University Hospital of Zurich · GR
Area of research
Oncology · Molecular Biology
Research interest
Research interests include Melanoma and MAPK Pathways, Cancer Immunotherapy and Biomarkers, Cutaneous Melanoma Detection and Management, and CAR-T cell therapy research.
h-index
74
citations
34,588
works
607
NIH funding
primary concept
email

Recent publications

Nivolumab plus relatlimab in advanced melanoma: RELATIVITY-047 4-year update
European Journal of Cancer 2025cited by 15position: middledoi
Cutaneous melanoma: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up
Annals of Oncology 2024cited by 126position: middledoi
Sequential immunotherapy and targeted therapy for metastatic BRAF V600 mutated melanoma: 4-year survival and biomarkers evaluation from the phase II SECOMBIT trial
Nature Communications 2024cited by 84position: middledoi
Three-Year Overall Survival With Nivolumab Plus Relatlimab in Advanced Melanoma From RELATIVITY-047
Journal of Clinical Oncology 2024cited by 57position: middledoi
Sequencing of Checkpoint or BRAF/MEK Inhibitors on Brain Metastases in Melanoma
NEJM Evidence 2024cited by 10position: middledoi
Overall Survival and Response with Nivolumab and Relatlimab in Advanced Melanoma
NEJM Evidence 2023cited by 123position: middledoi
Bempegaldesleukin Plus Nivolumab in Untreated Advanced Melanoma: The Open-Label, Phase III PIVOT IO 001 Trial Results
Journal of Clinical Oncology 2023cited by 68position: middledoi
The side effect registry immuno-oncology (SERIO) – A tool for systematic analysis of immunotherapy-induced side effects
European Journal of Cancer 2023cited by 15position: middledoi
Early switch from run-in treatment with vemurafenib plus cobimetinib to atezolizumab after 3 months leads to rapid loss of tumour control in patients with advanced BRAFV600-positive melanoma: The ImmunoCobiVem phase 2 randomised trial
European Journal of Cancer 2023cited by 14position: middledoi
A plain language summary of the 5-year update from part 1 of the COLUMBUS study: encorafenib and binimetinib for people with BRAF V600-mutant melanoma
Future Oncology 2023cited by 11position: middledoi
Randomized, Double-Blind, Placebo-Controlled, Global Phase III Trial of Talimogene Laherparepvec Combined With Pembrolizumab for Advanced Melanoma
Journal of Clinical Oncology 2022cited by 269position: lastdoi
Sequencing of Ipilimumab Plus Nivolumab and Encorafenib Plus Binimetinib for Untreated <i>BRAF</i>-Mutated Metastatic Melanoma (SECOMBIT): A Randomized, Three-Arm, Open-Label Phase II Trial
Journal of Clinical Oncology 2022cited by 215position: middledoi
COLUMBUS 5-Year Update: A Randomized, Open-Label, Phase III Trial of Encorafenib Plus Binimetinib Versus Vemurafenib or Encorafenib in Patients With<i>BRAF</i>V600–Mutant Melanoma
Journal of Clinical Oncology 2022cited by 183position: middledoi
Adjuvant Therapy of Nivolumab Combined With Ipilimumab Versus Nivolumab Alone in Patients With Resected Stage IIIB-D or Stage IV Melanoma (CheckMate 915)
Journal of Clinical Oncology 2022cited by 155position: middledoi
Randomized Phase III Trial Evaluating Spartalizumab Plus Dabrafenib and Trametinib for BRAF V600–Mutant Unresectable or Metastatic Melanoma
Zurich Open Repository and Archive (University of Zurich) 2022cited by 146position: middledoi
Overall survival with first-line atezolizumab in combination with vemurafenib and cobimetinib in BRAFV600 mutation-positive advanced melanoma (IMspire150): second interim analysis of a multicentre, randomised, phase 3 study
The Lancet Oncology 2022cited by 100position: middledoi
Relatlimab and nivolumab versus nivolumab in previously untreated metastatic or unresectable melanoma: Overall survival and response rates from RELATIVITY-047 (CA224-047)
Journal of Clinical Oncology 2022cited by 46position: middledoi
Biomarkers of treatment benefit with atezolizumab plus vemurafenib plus cobimetinib in BRAFV600 mutation–positive melanoma
Annals of Oncology 2022cited by 28position: middledoi
Efficacy and safety of sequencing with vemurafenib (V) plus cobimetinib (C) followed by atezolizumab (Atezo) in patients (pts) with advanced <i>BRAF<sup>V600</sup></i>-positive melanoma: Interim analysis of the ImmunoCobiVem study.
Journal of Clinical Oncology 2022cited by 7position: middledoi
Relatlimab (RELA) plus nivolumab (NIVO) versus NIVO in first-line advanced melanoma: Primary phase III results from RELATIVITY-047 (CA224-047).
Journal of Clinical Oncology 2021cited by 150position: middledoi
Talimogene laherparepvec upregulates immune-cell populations in non-injected lesions: findings from a phase II, multicenter, open-label study in patients with stage IIIB–IVM1c melanoma
Journal for ImmunoTherapy of Cancer 2021cited by 79position: lastdoi
1037O MASTERKEY-265: A phase III, randomized, placebo (Pbo)-controlled study of talimogene laherparepvec (T) plus pembrolizumab (P) for unresectable stage IIIB–IVM1c melanoma (MEL)
Annals of Oncology 2021cited by 57position: lastdoi
Regulatory T-cell Transcriptomic Reprogramming Characterizes Adverse Events by Checkpoint Inhibitors in Solid Tumors
Cancer Immunology Research 2021cited by 46position: middledoi
Five-year overall survival (OS) in COLUMBUS: A randomized phase 3 trial of encorafenib plus binimetinib versus vemurafenib or encorafenib in patients (pts) with <i>BRAF</i> V600-mutant melanoma.
Journal of Clinical Oncology 2021cited by 38position: middledoi
Abstract CT004: Adjuvant therapy with nivolumab (NIVO) combined with ipilimumab (IPI) vs NIVO alone in patients (pts) with resected stage IIIB-D/IV melanoma (CheckMate 915)
Cancer Research 2021cited by 36position: middledoi
Quality of life in patients with BRAF-mutant melanoma receiving the combination encorafenib plus binimetinib: Results from a multicentre, open-label, randomised, phase III study (COLUMBUS)
European Journal of Cancer 2021cited by 15position: firstdoi
Corrigendum to ‘Quality of life in patients with BRAF-mutant melanoma receiving the combination encorafenib plus binimetinib: Results from a multicentre, open-label, randomised, phase III study (COLUMBUS)’ [European Journal of Cancer 152 (2021) 116-128]
European Journal of Cancer 2021cited by 0position: firstdoi
Survie Globale (SG) à cinq ans dans l’étude COLUMBUS : un essai randomisé de phase 3 évaluant encorafénib plus binimétinib versus vémurafenib ou encorafénib chez les patients atteints d’un mélanome muté BRAF V600
Annales de Dermatologie et de Vénéréologie - FMC 2021cited by 0position: middledoi
Atezolizumab, vemurafenib, and cobimetinib as first-line treatment for unresectable advanced BRAFV600 mutation-positive melanoma (IMspire150): primary analysis of the randomised, double-blind, placebo-controlled, phase 3 trial
The Lancet 2020cited by 645position: middledoi
Five-Year Outcomes With Nivolumab in Patients With Wild-Type <i>BRAF</i> Advanced Melanoma
Journal of Clinical Oncology 2020cited by 223position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Dirk Schadendorf · Istituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori29 papers (2015–2025)Paolo A. Ascierto · Parker Institute for Cancer Immunotherapy27 papers (2015–2025)Ralf Gutzmer · University of Duisburg-Essen25 papers (2015–2023)Ana Arance · Grupo Español de Tumores Neuroendocrinos23 papers (2015–2025)Caroline Robert · Institut Gustave Roussy21 papers (2015–2023)Claus Garbe · STZ eyetrial19 papers (2015–2023)Mario Mandalà · Cancer Research UK Manchester Institute18 papers (2015–2023)Reinhard Dummer · Kantonsspital Aarau18 papers (2015–2023)Keith T. Flaherty · Boston Medical Center17 papers (2015–2023)Carmen Loquai · University Hospital and Clinics17 papers (2015–2023)Ivana Krajsová · General University Hospital in Prague15 papers (2017–2023)Gabriella Liszkay · National Institute of Oncology15 papers (2017–2023)Naoya Yamazaki · National Cancer Centre Japan13 papers (2017–2023)Caroline Dutriaux · Princess Alexandra Hospital12 papers (2015–2022) · 11 papers (2017–2021)Piotr Rutkowski · Maria Curie-Skłodowska University11 papers (2015–2025)Jean-Jacques Grob · Centre de Recherche en Cancérologie de Marseille10 papers (2015–2024)Jan Willem B. de Groot · Isala9 papers (2017–2023)Vanna Chiarion‐Sileni · Istituto Oncologico Veneto9 papers (2015–2021)Georgina V. Long · ARC Centre of Excellence in Synthetic Biology9 papers (2015–2025)