Area of research
Genetics · Pharmacology
Research interest
Research interests include Genomics and Rare Diseases, BRCA gene mutations in cancer, Pharmacogenetics and Drug Metabolism, and Astrophysics and Cosmic Phenomena.
Governing real-world health data as a public utility.
Characterizing trends in clinical genetic testing: A single-center analysis of EHR data from 1.8 million patients over two decades.
Covering medical care costs for participants in the eMERGE Network: Challenges for equity and implementation
Covering medical care costs for participants in the eMERGE Network: Challenges for equity and implementation.
Beyond Carrier Status: CFTR Heterozygosity as an Overlooked Clinical Risk Factor for Pancreatitis.
Implementing integrated genomic risk assessments for breast cancer: lessons learned from the Electronic Medical Records and Genomics study.
A standard-based taxonomy of features that affect user response to clinical decision support alerts.
Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations
Selection, optimization and validation of ten chronic disease polygenic risk scores for clinical implementation in diverse US populations.
Leveraging generative AI to prioritize drug repurposing candidates for Alzheimer’s disease with real-world clinical validation
Leveraging large language models for generating responses to patient messages-a subjective analysis.
Leveraging generative AI to prioritize drug repurposing candidates for Alzheimer's disease with real-world clinical validation.
Large language models facilitate the generation of electronic health record phenotyping algorithms.
Using large language model to guide patients to create efficient and comprehensive clinical care message.
Diagnostic delay in monogenic disease: A scoping review.
Leveraging explainable artificial intelligence to optimize clinical decision support.
Rationale and design for a pragmatic randomized trial to assess gene-based prescribing for SSRIs in the treatment of depression.
Implementing a pragmatic clinical trial to tailor opioids for chronic pain on behalf of the IGNITE ADOPT PGx investigators.
Pharmacogenomics: Genotype-Driven Medicine.
Returning integrated genomic risk and clinical recommendations: The eMERGE study.
Population Genomic Screening for Three Common Hereditary Conditions : A Cost-Effectiveness Analysis.
Evaluating and mitigating bias in machine learning models for cardiovascular disease prediction.
The phenotype-genotype reference map: Improving biobank data science through replication.
Familial Hypercholesterolemia in the Electronic Medical Records and Genomics Network: Prevalence, Penetrance, Cardiovascular Risk, and Outcomes After Return of Results.
Evaluation of the portability of computable phenotypes with natural language processing in the eMERGE network.
Studying the impact of translational genomic research: Lessons from eMERGE.
Prospective, multi-site study of healthcare utilization after actionable monogenic findings from clinical sequencing.
Phenotypic presentation of Mendelian disease across the diagnostic trajectory in electronic health records.
Scanning the medical phenome to identify new diagnoses after recovery from COVID-19 in a US cohort.
Risk factors affecting polygenic score performance across diverse cohorts