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Masakazu Toi

Universal Scientific Education and Research Network · JP
Area of research
Oncology · Cancer Research
Research interest
Research interests include Breast Cancer Treatment Studies, Advanced Breast Cancer Therapies, HER2/EGFR in Cancer Research, and Cancer Treatment and Pharmacology.
h-index
89
citations
45,507
works
1,133
NIH funding
primary concept
email

Recent publications

Trastuzumab Deruxtecan plus Pertuzumab for HER2-Positive Metastatic Breast Cancer
New England Journal of Medicine 2025cited by 30position: middledoi
Trastuzumab deruxtecan (T-DXd) + pertuzumab (P) vs taxane + trastuzumab + pertuzumab (THP) for first-line (1L) treatment of patients (pts) with human epidermal growth factor receptor 2–positive (HER2+) advanced/metastatic breast cancer (a/mBC): Interim results from DESTINY-Breast09.
Journal of Clinical Oncology 2025cited by 27position: middledoi
Final survival results from the PENELOPE-B trial investigating palbociclib versus placebo for patients with high-risk HR+/HER2− breast cancer and residual disease after neoadjuvant chemotherapy
Annals of Oncology 2025cited by 17position: middledoi
Mechanisms of sensitivity and resistance to CDK4/CDK6 inhibitors in hormone receptor-positive breast cancer treatment
Drug Resistance Updates 2024cited by 53position: middledoi
Capivasertib and fulvestrant for patients with hormone receptor-positive, HER2-negative advanced breast cancer (CAPItello-291): patient-reported outcomes from a phase 3, randomised, double-blind, placebo-controlled trial
The Lancet Oncology 2024cited by 38position: middledoi
Patient-Reported Outcomes in OlympiA: A Phase III, Randomized, Placebo-Controlled Trial of Adjuvant Olaparib in g<i>BRCA1/2</i> Mutations and High-Risk Human Epidermal Growth Factor Receptor 2–Negative Early Breast Cancer
Journal of Clinical Oncology 2024cited by 11position: middledoi
Early breast cancer: ESMO Clinical Practice Guideline for diagnosis, treatment and follow-up
Annals of Oncology 2023cited by 793position: middledoi
Capivasertib in Hormone Receptor–Positive Advanced Breast Cancer
New England Journal of Medicine 2023cited by 680position: middledoi
Evolutionary histories of breast cancer and related clones
Nature 2023cited by 79position: middledoi
Landscape of Baseline and Acquired Genomic Alterations in Circulating Tumor DNA with Abemaciclib Alone or with Endocrine Therapy in Advanced Breast Cancer
Clinical Cancer Research 2023cited by 38position: middledoi
Abstract GS3-04: GS3-04 Capivasertib and fulvestrant for patients with aromatase inhibitor-resistant hormone receptor-positive/human epidermal growth factor receptor 2-negative advanced breast cancer: results from the Phase III CAPItello-291 trial
Cancer Research 2023cited by 30position: middledoi
Abemaciclib plus endocrine therapy for hormone receptor-positive, HER2-negative, node-positive, high-risk early breast cancer (monarchE): results from a preplanned interim analysis of a randomised, open-label, phase 3 trial
The Lancet Oncology 2022cited by 546position: middledoi
Overall survival in the OlympiA phase III trial of adjuvant olaparib in patients with germline pathogenic variants in BRCA1/2 and high-risk, early breast cancer
Annals of Oncology 2022cited by 433position: middledoi
Adjuvant abemaciclib combined with endocrine therapy for high-risk early breast cancer: safety and patient-reported outcomes from the monarchE study
Annals of Oncology 2022cited by 122position: middledoi
ATM suppresses c-Myc overexpression in the mammary epithelium in response to estrogen
Cell Reports 2022cited by 11position: middledoi
Factors affecting prognosis in patients treated with bevacizumab plus paclitaxel as first-line chemotherapy for HER2-negative metastatic breast cancer: an international pooled analysis of individual patient data from four prospective observational studies
Breast Cancer 2022cited by 3position: middledoi
Customizing local and systemic therapies for women with early breast cancer: the St. Gallen International Consensus Guidelines for treatment of early breast cancer 2021
Annals of Oncology 2021cited by 792position: middledoi
Adjuvant abemaciclib combined with endocrine therapy for high-risk early breast cancer: updated efficacy and Ki-67 analysis from the monarchE study
Annals of Oncology 2021cited by 374position: middledoi
Adjuvant Pertuzumab and Trastuzumab in Early HER2-Positive Breast Cancer in the APHINITY Trial: 6 Years' Follow-Up
Journal of Clinical Oncology 2021cited by 354position: middledoi
Safety and efficacy of abemaciclib plus endocrine therapy in older patients with hormone receptor-positive/human epidermal growth factor receptor 2-negative advanced breast cancer: an age-specific subgroup analysis of MONARCH 2 and 3 trials
Breast Cancer Research and Treatment 2021cited by 55position: middledoi
Updated results from the international phase III ALTTO trial (BIG 2-06/Alliance N063D)
European Journal of Cancer 2021cited by 28position: middledoi
Genetic and clinical landscape of breast cancers with germline BRCA1/2 variants
Communications Biology 2020cited by 38position: lastdoi
311P Pooled-analysis of prospective observational studies evaluated the effectiveness and safety of bevacizumab and paclitaxel as the first-line chemotherapy for HER2-negative metastatic breast cancer
Annals of Oncology 2020cited by 0position: middledoi
Insights Into Breast Cancer in the East vs the West
JAMA Oncology 2019cited by 185position: middledoi
Trastuzumab emtansine with or without pertuzumab versus trastuzumab with taxane for human epidermal growth factor receptor 2–positive advanced breast cancer: Final results from MARIANNE
Cancer 2019cited by 113position: middledoi
BRCA1 ensures genome integrity by eliminating estrogen-induced pathological topoisomerase II–DNA complexes
Proceedings of the National Academy of Sciences 2018cited by 108position: middledoi
De-escalating and escalating treatments for early-stage breast cancer: the St. Gallen International Expert Consensus Conference on the Primary Therapy of Early Breast Cancer 2017
Annals of Oncology 2017cited by 1,251position: middledoi
Efficacy and safety of everolimus in combination with trastuzumab and paclitaxel in Asian patients with HER2+ advanced breast cancer in BOLERO-1
Breast Cancer Research 2017cited by 32position: firstdoi
Toxicity profile differences of adjuvant docetaxel/cyclophosphamide (TC) between Asian and Caucasian breast cancer patients
Asia-Pacific Journal of Clinical Oncology 2017cited by 25position: lastdoi
Tailoring therapies—improving the management of early breast cancer: St Gallen International Expert Consensus on the Primary Therapy of Early Breast Cancer 2015
Annals of Oncology 2015cited by 1,832position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Qingyuan Zhang · The Seventh Affiliated Hospital of Sun Yat-sen University5 papers (2015–2025)Louis W.C. Chow · Macau University of Science and Technology5 papers (2012–2017)Zefei Jiang · University of Sydney5 papers (2015–2025)Hope S. Rugo · UCSF Helen Diller Family Comprehensive Cancer Center5 papers (2022–2024)Miguel Martín · Spanish Ovarian Cancer Research Group4 papers (2019–2025)Javier Cortés · Universidade Nova de Lisboa4 papers (2023–2024)Sara A. Hurvitz · University of Washington Applied Physics Laboratory4 papers (2015–2023)Sara M. Tolaney · Medidata (United States)4 papers (2022–2025)Meena Okera · Cancer Council SA4 papers (2021–2024)Mario Campone · Centre de Recherche en Cancérologie de Lyon4 papers (2021–2023)Kunwei Shen · Shanghai Jiao Tong University4 papers (2014–2017)Andreas Schneeweiß · NSABP Foundation4 papers (2020–2025)Xichun Hu · Shanghai Medical College of Fudan University3 papers (2023–2024)Wings T.Y. Loo · Hong Kong Polytechnic University3 papers (2012–2017)Belén San Antonio · Eli Lilly (United States)3 papers (2021–2022)Tetiana Taran · Lublin Oncology Center3 papers (2014–2015)Fabrice André · Institut Gustave Roussy3 papers (2014–2015)Donggeng Liu · Sun Yat-sen University3 papers (2015–2017)Matthew P. Goetz · Mayo Clinic3 papers (2021–2023)Hironobu Sasano · Tohoku University3 papers (2012–2012)