Area of research
Biomaterials · Biomedical Engineering
Research interest
Research interests include Nanoparticle-Based Drug Delivery, Nanoplatforms for cancer theranostics, CAR-T cell therapy research, and Immunotherapy and Immune Responses.
Charge-reversal proteolysis polymers enable tissue-specific STING degradation in rheumatoid arthritis.
Genetic engineering of systemically injectable oncolytic viruses for pyroptosis-accelerated cancer virotherapy.
Lipid metabolism drives dietary effects on T cell ferroptosis and immunity.
Exploration of Orally Disintegrating Tablet for Sublingual Vaccination against Mucosal Bacterial Infection
Ferritin aggregation cell engager for CAR T avidity engineering against refractory leukemias
Engineered Bacteria Manipulate Cysteine Metabolism to Boost Ferroptosis-Based Pancreatic Ductal Adenocarcinoma Therapy.
Macrophage-specific in vivo RNA editing promotes phagocytosis and antitumor immunity in mice.
MLKL as an emerging machinery for modulating organelle dynamics: regulatory mechanisms, pathophysiological significance, and targeted therapeutics
Versatile PLGA-Based Drug Delivery Systems for Tumor Immunotherapy.
<i>Fusobacterium nucleatum</i> in Colorectal Cancer: Ally Mechanism and Targeted Therapy Strategies.
Cationic alkyl chain length and nanoaggregate form of ionic liquids dominate biocompatibility and toxicity.
Selenized neural stem cell-derived exosomes: A neotype therapeutic agent for traumatic injuries of the central nervous system
Nanoformulation-based drug delivery systems for the treatment of gastric cancer: recent developments and future prospects.
Microcarrier stiffness controls human amniotic epithelial cells (hAECs) proliferation and epithelial-mesenchymal transition (EMT) via remodeling ECM and Wnt/β-catenin pathway
An oncolytic virus-T cell chimera for cancer immunotherapy.
Exosome-loaded degradable polymeric microcapsules for the treatment of vitreoretinal diseases.
Nose-to-brain delivery of nanotherapeutics: Transport mechanisms and applications.
Microneedle patch loaded with ferritin-nanocaged doxorubicin for locally targeted drug delivery and efficient skin cancer treatment
Advances of Bacterial Biomaterials for Disease Therapy.
PKC-θ is an important driver of fluoride-induced immune imbalance of regulatory T cells/effector T cells
Lysosomal "TRAP": a neotype modality for clearance of viruses and variants.
PEGylated graphene oxide-mediated stimulation of vascular endothelial cells and responsive release of PD-1/PD-L1 inhibitor for efficient chemo-immunotherapy against cancer
PKC-Θ is an Important Driver of Fluoride-Induced Immune Imbalance of Regulatory T Cells/Effector T Cells
Virtual Monoenergetic Images Facilitate Better Identification of the Arc of Riolan During Splenic Flexure Takedown
Inhaled SARS-CoV-2 vaccine for single-dose dry powder aerosol immunization.
A Targeted Exosome Therapeutic Confers Both CfDNA Scavenging and Macrophage Polarization for Ameliorating Rheumatoid Arthritis.
Non-invasive activation of intratumoural gene editing for improved adoptive T-cell therapy in solid tumours.
Generation of whole tumor cell vaccine for on-demand manipulation of immune responses against cancer under near-infrared laser irradiation.
Ionic liquids revolutionizing biomedicine: recent advances and emerging opportunities.
Maximizing the pozzolanic potential of superfine iron tailings for low-carbon stabilization: Application of high-calcium geopolymer