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Li Shen

Xuchang University · CN
Area of research
Molecular Biology · Psychiatry and Mental health
Research interest
Research interests include Bioinformatics and Genomic Networks, Dementia and Cognitive Impairment Research, Functional Brain Connectivity Studies, and Alzheimer's disease research and treatments.
h-index
82
citations
32,882
works
1,162
NIH funding
$745K
primary concept
email

Recent publications

A survey on privacy risks and protection in large language models
Journal of King Saud University - Computer and Information Sciences 2025cited by 18position: middledoi
SDoH-GPT: using large language models to extract social determinants of health
Journal of the American Medical Informatics Association 2025cited by 11position: middledoi
Effects of Continuous Positive Airway Pressure on Neuroimaging Biomarkers and Cognition in Adult Obstructive Sleep Apnea: A Randomized Controlled Trial
American Journal of Respiratory and Critical Care Medicine 2025cited by 11position: middledoi
Neuroimaging endophenotypes reveal underlying mechanisms and genetic factors contributing to progression and development of four brain disorders
Nature Biomedical Engineering 2025cited by 10position: middledoi
Major-depressive-disorder-associated dysregulation of ZBTB7A in orbitofrontal cortex promotes astrocyte-mediated stress susceptibility
Neuron 2025cited by 5position: middledoi
3D Brain Vascular Niche Model Captures Glioblastoma Infiltration, Dormancy, and Gene Signatures
Advanced Science 2025cited by 3position: middledoi
Multiomics analysis to explore blood metabolite biomarkers in an Alzheimer’s Disease Neuroimaging Initiative cohort
Scientific Reports 2024cited by 26position: middledoi
Genetic and clinical correlates of two neuroanatomical AI dimensions in the Alzheimer’s disease continuum
Translational Psychiatry 2024cited by 20position: middledoi
A novel spatiotemporal graph convolutional network framework for functional connectivity biomarkers identification of Alzheimer’s disease
Alzheimer s Research & Therapy 2024cited by 17position: middledoi
Design and synthesis of piperine-based photoaffinity probes for revealing potential targets of piperine in neurological disease
Chemical Communications 2024cited by 3position: firstdoi
Volume-Optimal Persistence Homological Scaffolds of Hemodynamic Networks Covary with MEG Theta-Alpha Aperiodic Dynamics
Lecture notes in computer science 2024cited by 2position: lastdoi
[<i>Euphorbia helioscopia</i> inhibits proliferation, invasion, and migration and promotes apoptosis of non-small cell lung cancer cells].
PubMed 2024cited by 1position: middledoi
3D Brain Vascular Niche Model Captures Invasive Behavior and Gene Signatures of Glioblastoma
bioRxiv (Cold Spring Harbor Laboratory) 2024cited by 0position: middledoi
Deep learning-based polygenic risk analysis for Alzheimer’s disease prediction
Communications Medicine 2023cited by 69position: middledoi
Prevalence and Clinical Implications of a β-Amyloid–Negative, Tau-Positive Cerebrospinal Fluid Biomarker Profile in Alzheimer Disease
JAMA Neurology 2023cited by 43position: middledoi
Genomic loci influence patterns of structural covariance in the human brain
Proceedings of the National Academy of Sciences 2023cited by 36position: middledoi
Hypoxia induces the production of epithelial-derived cytokines in eosinophilic chronic rhinosinusitis with nasal polyps
International Immunopharmacology 2023cited by 13position: middledoi
Hypoxia disrupts the nasal epithelial barrier by inhibiting PTPN2 in chronic rhinosinusitis with nasal polyps
International Immunopharmacology 2023cited by 11position: middledoi
Diagnostic value and underlying mechanism of nasal nitric oxide in eosinophilic chronic rhinosinusitis with nasal polyps
Molecular Immunology 2023cited by 11position: middledoi
Histone H3 serotonylation dynamics in dorsal raphe nucleus contribute to stress- and antidepressant-mediated gene expression and behavior
bioRxiv (Cold Spring Harbor Laboratory) 2023cited by 7position: middledoi
Characterizing Heterogeneity in Neuroimaging, Cognition, Clinical Symptoms, and Genetics Among Patients With Late-Life Depression
JAMA Psychiatry 2022cited by 145position: middledoi
Amyloid-associated increases in soluble tau relate to tau aggregation rates and cognitive decline in early Alzheimer’s disease
Nature Communications 2022cited by 129position: middledoi
The trend of disruption in the functional brain network topology of Alzheimer’s disease
Scientific Reports 2022cited by 40position: middledoi
Primary surgery followed by selective radiochemotherapy versus conventional preoperative radiochemotherapy for patients with locally advanced rectal cancer with MRI-negative circumferential margin (PSSR): A multicenter, randomized, open-label, noninferiority, phase 3 trial.
Journal of Clinical Oncology 2022cited by 2position: lastdoi
Additional file 1 of Identifying genetic markers enriched by brain imaging endophenotypes in Alzheimer’s disease
Figshare 2022cited by 0position: lastdoi
Additional file 2 of Deep multiview learning to identify imaging-driven subtypes in mild cognitive impairment
Open MIND 2022cited by 0position: lastdoi
Longitudinal Associations of Blood Phosphorylated Tau181 and Neurofilament Light Chain With Neurodegeneration in Alzheimer Disease
JAMA Neurology 2021cited by 319position: middledoi
Accelerated functional brain aging in pre-clinical familial Alzheimer’s disease
Nature Communications 2021cited by 100position: middledoi
A deep learning framework identifies dimensional representations of Alzheimer’s Disease from brain structure
Nature Communications 2021cited by 99position: middledoi
A <scp>meta‐analysis</scp> of deep brain structural shape and asymmetry abnormalities in 2,833 individuals with schizophrenia compared with 3,929 healthy volunteers via the <scp>ENIGMA Consortium</scp>
Human Brain Mapping 2021cited by 75position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

Andrew J. Saykin · Vanderbilt University Medical Center15 papers (2012–2022)Shannon L. Risacher · Wake Forest University10 papers (2012–2015)Sungeun Kim · Korea University9 papers (2012–2015)Michael W. Weiner · Hôpital Beau-Séjour8 papers (2012–2015)Kwangsik Nho · Indiana University Bloomington8 papers (2012–2015)Tatiana Foroud · University of Wisconsin–Madison7 papers (2012–2015)Paul Aisen · University of Southern California6 papers (2012–2015)Ronald C. Petersen · University Hospital Leipzig6 papers (2012–2015)Robert C. Green · Broad Institute5 papers (2013–2015)Clifford R. Jack · ADS Group5 papers (2013–2015)Arthur W. Toga · UtopiaCompression (United States)5 papers (2013–2015)Vijay K. Ramanan · Mayo Clinic in Arizona5 papers (2012–2015)William J. Jagust · Berkeley College5 papers (2013–2015)Leslie M. Shaw · Siemens (United States)4 papers (2013–2015)Shanker Swaminathan · Baylor College of Medicine4 papers (2012–2013)Junhao Tu · Nanchang University4 papers (2020–2023)Jing Ye · Nanchang University3 papers (2023–2023)Meiping Zhang · Nanchang University3 papers (2023–2023)John Q. Trojanowski · University of Pennsylvania3 papers (2013–2015)Holly Soares · Pfizer (United States)3 papers (2013–2015)