Area of research
Pharmacology · Pulmonary and Respiratory Medicine
Research interest
Research interests include Microbial Natural Products and Biosynthesis, Prostate Cancer Treatment and Research, Fungal Biology and Applications, and Advanced Breast Cancer Therapies.
Preparation, Physicochemical Properties and Stability of Anthocyanin Nanoliposomes Before and After Double-Layer Modification Using Synanthrin and Pea Protein Isolate
Mediator kinase inhibition reverses castration resistance of advanced prostate cancer.
Jiawei Qi Gong Wan improves liver fibrosis and inflammation in PCOS mice via the Akt2-FoxO1 and YAP/TAZ signaling pathways
Mediator kinase inhibitors suppress triple-negative breast cancer growth and extend tumor suppression by mTOR and AKT inhibitors.
CDK8 and CDK19: positive regulators of signal-induced transcription and negative regulators of Mediator complex proteins.
CDK19 and CDK8 Mediator kinases drive androgen-independent <i>in vivo</i> growth of castration-resistant prostate cancer
CDK8/19 Inhibition Attenuates G1 Arrest Induced by BCR-ABL Antagonists and Accelerates Death of Chronic Myelogenous Leukemia Cells
Knockout of cyclin dependent kinases 8 and 19 leads to depletion of cyclin C and suppresses spermatogenesis and male fertility in mice
Inhibition of CDK8/19 Mediator kinase potentiates HER2-targeting drugs and bypasses resistance to these agents in vitro and in vivo.
A Selective and Orally Bioavailable Quinoline-6-Carbonitrile-Based Inhibitor of CDK8/19 Mediator Kinase with Tumor-Enriched Pharmacokinetics.
Antimicrobial Chlorinated Carbazole Alkaloids from the <scp>Sponge‐Associated</scp> Actinomycete <i>Streptomyces diacarni</i><scp>LHW51701</scp>
Abstract PS15-10: Survival outcomes and prognosis for patients with triple negative breast cancer who received stereotactic radiosurgery for brain metastases
Uncovering the anticancer mechanism of petroleum extracts of Farfarae Flos against Lewis lung cancer by metabolomics and network pharmacology analysis
Systemic Toxicity Reported for CDK8/19 Inhibitors CCT251921 and MSC2530818 Is Not Due to Target Inhibition.
Clinical and genetic risk factors for Fulvestrant treatment in post-menopause ER-positive advanced breast cancer patients
Characterizing CDK8/19 Inhibitors through a NFκB-Dependent Cell-Based Assay.
Identification of Personalized Chemoresistance Genes in Subtypes of Basal-Like Breast Cancer Based on Functional Differences Using Pathway Analysis
Koninginins L and M, two polyketides from Trichoderma koningii 8662
Antimicrobial Aromatic Polyketides from Gorgonian‐Associated Fungus, <i>Penicillium commune </i>518
CAREER: Computationally Illuminating the Molecular Interplay between N-glycosylation and Ion Channel Gating
CAREER: Towards Safety-Critical Real-Time Systems with Learning Components
Collaborative Research: SAI: Planning for Electric Vehicle Charging Infrastructure
NSF-BSF: Collaborative Research: Market Conduct in Technology Adoption in the Automobile Industry
Collaborative Research: RUI: Structured Population Dynamics Subject to Stoichiometric Constraints
PIPP Phase I: Comprehensive, Integrated, Intelligent System for Early and Accurate Pandemic Prediction, Prevention, and Preparation at Personal and Population Levels
NSF-BSF: Collaborative Research: Market Conduct in Technology Adoption in the Automobile Industry
Inverse Mapping of Spatial-Temporal Molecular Heterogeneity from Imaging Phenotype
CAREER: Associative In-Memory Graph Processing Paradigm: Towards Tera-TEPS Graph Traversal In a Box
FET: CCF: Small: Computational Drug Prediction through Joint Learning
CRII: CSR: Enabling Efficient Real-Time Systems upon Multiple Parallel Resources
RAPID:Genomic Variation Analysis of Coronavirus to Better Understand the Spread of COVID-19
Inverse Mapping of Spatial-Temporal Molecular Heterogeneity from Imaging Phenotype
CAREER: Associative In-Memory Graph Processing Paradigm: Towards Tera-TEPS Graph Traversal In a Box
AF: Small: Homogeneous and Heterogeneous Network Learning with Applications in Computational Biology
Developing Highly Luminescent Materials for Low-Cost and Energy-Efficient Lighting Applications
EARS: Enhancing Spectrum Efficiency of Autonomous and Agile Hybrid FSO/RF Systems
Crystalline Hybrid Semiconductors: A systematic Approach to Develop Nanostructured Materials with Enhanced Properties and New Functionality
CAREER: Transfer Learning Based Quality Improvement in Spatially-Temporally Complex Systems
A Conference on New Frontiers in Numerical Analysis and Scientific Computing