Area of research
Molecular Biology · Cardiology and Cardiovascular Medicine
Research interest
Research interests include Ion channel regulation and function, Cardiac electrophysiology and arrhythmias, Signaling Pathways in Disease, and Protein Structure and Dynamics.
Therapeutic Potential of Terpenoids in Cancer Treatment: Targeting Mitochondrial Pathways
A distinct mechanism of C-type inactivation in the Kv-like KcsA mutant E71V
Mechanism of C-type inactivation in the hERG potassium channel
Further Optimization and Validation of the Classical Drude Polarizable Protein Force Field
Open and Closed Structures of a Barium-Blocked Potassium Channel
Functional implications of miR-145/RCAN3 axis in the progression of cervical cancer
Allostery in Its Many Disguises: From Theory to Applications
Shifts in the selectivity filter dynamics cause modal gating in K+ channels
Binding partner- and force-promoted changes in αE-catenin conformation probed by native cysteine labeling
Locking Two Rigid-body Bundles in an Outward-Facing Conformation: The Ion-coupling Mechanism in a LeuT-fold Transporter
Dynamic allostery can drive cold adaptation in enzymes
Rapid constriction of the selectivity filter underlies C-type inactivation in the KcsA potassium channel
Chemical substitutions in the selectivity filter of potassium channels do not rule out constricted-like conformations for C-type inactivation
ADAM17 participates in the protective effect of paeoniflorin on mouse brain microvascular endothelial cells
TAK1 Regulates Myocardial Response to Pathological Stress via NFAT, NFκB and Bnip3 Pathways
The ensemble nature of allostery
CAREER: Computationally Illuminating the Molecular Interplay between N-glycosylation and Ion Channel Gating
CAREER: Towards Safety-Critical Real-Time Systems with Learning Components
Collaborative Research: RUI: Structured Population Dynamics Subject to Stoichiometric Constraints
PIPP Phase I: Comprehensive, Integrated, Intelligent System for Early and Accurate Pandemic Prediction, Prevention, and Preparation at Personal and Population Levels
Inverse Mapping of Spatial-Temporal Molecular Heterogeneity from Imaging Phenotype
CAREER: Associative In-Memory Graph Processing Paradigm: Towards Tera-TEPS Graph Traversal In a Box
FET: CCF: Small: Computational Drug Prediction through Joint Learning
CRII: CSR: Enabling Efficient Real-Time Systems upon Multiple Parallel Resources
RAPID:Genomic Variation Analysis of Coronavirus to Better Understand the Spread of COVID-19
Inverse Mapping of Spatial-Temporal Molecular Heterogeneity from Imaging Phenotype
CAREER: Associative In-Memory Graph Processing Paradigm: Towards Tera-TEPS Graph Traversal In a Box
AF: Small: Homogeneous and Heterogeneous Network Learning with Applications in Computational Biology
Developing Highly Luminescent Materials for Low-Cost and Energy-Efficient Lighting Applications
EARS: Enhancing Spectrum Efficiency of Autonomous and Agile Hybrid FSO/RF Systems
Crystalline Hybrid Semiconductors: A systematic Approach to Develop Nanostructured Materials with Enhanced Properties and New Functionality
CAREER: Transfer Learning Based Quality Improvement in Spatially-Temporally Complex Systems
A Conference on New Frontiers in Numerical Analysis and Scientific Computing