Area of research
Economics and Econometrics · Gender Studies
Research interest
Research topics from publications: Mechanistic study on the role of multi-pathway autophagy in ovarian aging: literature review; Mechanisms and treatment modalities related to premature ovarian insufficiency in mitochondria: literature review. Representative work: Premature ovarian insufficiency (POI) is a common, heterogeneous disorder that affects up to 3.5% of women under 40 years of age and is defined by oligo/amenorrhoea, hypo-oestrogenism, and markedly elevated gonadotrophin levels. POI substantially increases risks for infertility, osteoporosis, cardiovascular disease, and psychological morbidity; however, its precise aetiology remains elusive, and current therapies rarely restore lasting ovarian function. This review synthesizes recent molecular, cellular, and animal data to clarify how six facets of mitochondrial dysregulation: oxidative stress, imbalanced dynamics (fusion/fission/mitophagy), defective biogenesis, altered mitochondrial DNA (c