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Weidong Chen

National Institutes of Health · US
Area of research
Complementary and alternative medicine · Oncology
Research interest
Research interests include Traditional Chinese Medicine Analysis, Drug Transport and Resistance Mechanisms, Nanoparticle-Based Drug Delivery, and Gastric Cancer Management and Outcomes.
h-index
56
citations
13,173
works
562
NIH funding
primary concept
email

Recent publications

Application of hybrid exosomes-mediated targeted delivery system for sinomenine hydrochloride in rheumatoid arthritis therapy.
2026cited by 0position: contributordoi
Simultaneous Determination of HuoXueJieGu Decoction Chemical Composition, Plasma Components, and Tissue Distribution by Ultra‐High‐Performance Liquid Chromatography‐Quadrupole‐Orbitrap Mass Spectrometry
SEPARATION SCIENCE PLUS 2026cited by 0position: contributordoi
Ershen Zhenwu Decoction suppresses myocardial fibrosis of chronic heart failure with heart-kidney Yang deficiency by down-regulating the Ras Homolog Gene Family Member A/Rho-Associated Coiled-Coil Kinases signaling pathway.
2025cited by 6position: contributordoi
Activation of pregnane X receptor-organic anion transporting polypeptide 1a/b /P-glycoprotein/multidrug resistance protein 2 axis mediates the accelerated blood and liver clearance of PEGylated liposomes.
2025cited by 0position: contributordoi
Dendrobium huoshanense in the treatment of ulcerative colitis: Network pharmacology and experimental validation.
2024cited by 13position: contributordoi
Controlled release of vitamin A palmitate from crosslinked cyclodextrin organic framework for dry eye disease therapy
International Journal of Pharmaceutics 2024cited by 10position: middledoi
Comparative efficacy of sweated and non-sweated Salvia miltiorrhiza Bge. extracts on acute myocardial ischemia via regulating the PPARα/RXRα/NF-κB signaling pathway
Heliyon 2024cited by 6position: contributordoi
Novel dual targeting cubosomes modified with angiopep-2 for co-delivery GNA and PLHSpT to brain glioma.
2024cited by 3position: contributordoi
Characterization and quality evaluation of QiXueShuFu Decoction based on fingerprint and ultra-performance liquid chromatography-quadrupole-orbitrap mass spectrometry.
2024cited by 2position: contributordoi
Abstract 4360: Integrative analysis of multiplex interphase FISH copy number with whole exome sequencing identifies tumor evolution in Stage II colon cancer
Cancer Research 2024cited by 0position: middledoi
Tai Chi for fall prevention and balance improvement in older adults: a systematic review and meta-analysis of randomized controlled trials
Frontiers in Public Health 2023cited by 49position: firstdoi
Exosomes as biomarkers and therapeutic measures for ischemic stroke.
2023cited by 6position: contributordoi
Novel dual targeting cubosomes modified with angiopep-2 for co-delivery GNA and PLHSpT to brain glioma
Journal of Biomaterials Applications 2023cited by 4position: middledoi
Single-cell transcriptome profiling of the human endometrium of patients with recurrent implantation failure
Theranostics 2022cited by 103position: middledoi
Targeting ZFP64/GAL-1 axis promotes therapeutic effect of nab-paclitaxel and reverses immunosuppressive microenvironment in gastric cancer
Journal of Experimental & Clinical Cancer Research 2022cited by 48position: middledoi
Phytochemical profile and protective effects on myocardial ischaemia-reperfusion injury of sweated and non-sweated Salvia miltiorrhiza. Bge alcoholic extracts.
2022cited by 5position: contributordoi
Extracellular vesicles-encapsulated microRNA in mammalian reproduction: A review
Theriogenology 2022cited by 5position: middledoi
Evaluation of Zuo-Gui Yin Decoction Effects on Six CYP450 Enzymes in Rats Using a Cocktail Method by UPLC-MS/MS.
2022cited by 1position: contributordoi
Single-cell analysis reveals transcriptomic remodellings in distinct cell types that contribute to human prostate cancer progression
Nature Cell Biology 2021cited by 529position: middledoi
Research Progress of Therapeutic Enzymes and Their Derivatives: Based on Herbal Medicinal Products in Rheumatoid Arthritis
Frontiers in Pharmacology 2021cited by 17position: middledoi
Identification and Analysis of Chemical Constituents and Rat Serum Metabolites in Gushuling Using UPLC-Q-TOF/MS Coupled with Novel Informatics UNIFI Platform.
2021cited by 7position: contributordoi
Effects of mulberry leaf extracts on activity and mRNA expression of five cytochrome P450 enzymes in rat
Brazilian Journal of Pharmaceutical Sciences 2021cited by 1position: contributordoi
Acidity and Glutathione Dual-Responsive Polydopamine-Coated Organic-Inorganic Hybrid Hollow Mesoporous Silica Nanoparticles for Controlled Drug Delivery.
2020cited by 23position: contributordoi
Evaluation of Zhenwu Decoction Effects on CYP450 Enzymes in Rats Using a Cocktail Method by UPLC-MS/MS.
2020cited by 5position: contributordoi
Effect of You-Gui Yin on the Activities of Seven Cytochrome P450 Isozymes in Rats.
2020cited by 4position: contributordoi
A "Ship-in-a-Bottle" strategy to create folic acid nanoclusters inside the nanocages of γ-cyclodextrin metal-organic frameworks.
2019cited by 48position: contributordoi
The IGCA staging system is more accurate than AJCC7 system in stratifying survival of patients with gastric cancer in stage III
BMC Cancer 2017cited by 38position: middledoi
Combined analysis of O6-methylguanine-DNA methyltransferase protein expression and promoter methylation provides optimized prognostication of glioblastoma outcome
Neuro-Oncology 2013cited by 116position: middledoi
Lyophilized brain tumor specimens can be used for histologic, nucleic acid, and protein analyses after 1 year of room temperature storage
Journal of Neuro-Oncology 2013cited by 33position: middledoi
Overexpression of isocitrate dehydrogenase mutant proteins renders glioma cells more sensitive to radiation
Neuro-Oncology 2012cited by 152position: middledoi

Grants

Routing Support for Wireless and Mobile Applications
NSF9628126$315,1671996–1999PIRePORTER
Phylogenetic Relationships Among Freshwater and Marine Ascomycetes
NSF9508992$120,0001995–1998PIRePORTER
Query Processing in Knowledge Base Systems
NSF9314897$65,0001994–1997PIRePORTER
Reasoning About Database Updates
NSF9212074$94,0001992–1996PIRePORTER

Frequent collaborators

· 17 papers (2019–2026)Lei Wang · China Pharmaceutical University4 papers (2021–2026)Zhenbin Shen · Sun Yat-sen University3 papers (2012–2022)Albert Lai · APLA Health3 papers (2012–2013)Timothy F. Cloughesy · UCLA Medical Center3 papers (2012–2013)Linda M. Liau · The University of Texas Southwestern Medical Center3 papers (2012–2013)Fenglin Liu · Fudan University Shanghai Cancer Center2 papers (2012–2017)Xuefei Wang · Dalian Medical University2 papers (2012–2017)Desiree E. Sanchez · University of Southern California2 papers (2012–2013)Caiyun Zhang · Springer Nature2 papers (2021–2022)Ryan W. Wilson · Kaiser Permanente2 papers (2012–2013)Arthur P. Chou · University of California, Los Angeles2 papers (2012–2012)William H. Yong · University of California, Irvine2 papers (2012–2013)Yihong Sun · South China Agricultural University2 papers (2012–2017)Paul S. Mischel · Stanford Health Care2 papers (2012–2013)Jerry J. Lou · University of California, Los Angeles2 papers (2012–2013)Julia M. Selfridge · University of North Carolina at Chapel Hill2 papers (2012–2012)Yun Wang · Nanchang University1 papers (2022–2022)Ce Zhang · University of North Carolina at Chapel Hill1 papers (2022–2022)Cong Wang · Wenzhou Medical University1 papers (2012–2012)