Area of research
Immunology · Epidemiology
Research interest
Research interests include Immune Cell Function and Interaction, Liver Disease Diagnosis and Treatment, T-cell and B-cell Immunology, and Liver physiology and pathology.
Simvastatin Alleviates ConA-Induced Autoimmune Hepatitis by Inhibiting CD4<sup>+</sup> T Cell Activation via Calcium-NFATC3 Pathway.
Lactate attenuates hepatic ischemia-reperfusion injury by reducing intrahepatic inflammation and suppressing hepatocyte-neutrophil interaction via the IL-33/ST2 pathway.
FcεRIγ Reinforces Double-Negative T cell-mediated Antibody-dependent Cellular Cytotoxicity Against Tumor Cells.
Therapeutic Potential of TCRαβ<sup>+</sup>CD4<sup>-</sup>CD8<sup>-</sup> T Cells in Periodontitis.
The heterogeneity and sexual-dimorphism of human TCRαβ+CD4–CD8–double negative T cells
CD36-mediated uptake of oxidized LDL induces double-negative regulatory T cell ferroptosis in metabolic dysfunction-associated steatotic liver disease.
The direct and indirect inhibition of proinflammatory adipose tissue macrophages by acarbose in diet-induced obesity.
Purinergic signaling by TCRαβ<sup>+</sup> double-negative T regulatory cells ameliorates liver ischemia-reperfusion injury.
Genetic evidence for the liver-brain axis: lipid metabolism and neurodegenerative disease risk.
An atlas of early human mandibular endochondral and osteogenic paracrine signaling regions of Meckel's cartilage.
Perforin Generated by CD8<sup>+</sup> T Cells Exacerbates Inflammatory Bowel Disease-Induced Depression by Promoting CXCL9 Production in Intestinal Epithelial Cells.
Integrated multi-omics profiling characterizes the crucial role of human dental epithelium during tooth development.
Estrogen deficiency impairs double-negative T cell function and activates NF-κB in postmenopausal osteoporosis
Sodium nitrate protects against metabolic syndrome by sialin-mediated macrophage rebalance.
Red Meat Diet Exacerbates Colitis by Promoting the Accumulation of Myeloid Cells and Disrupting Gut Microbiota
SLAMF7 promotes TCRαβ<sup>+</sup> double negative T cell antitumor activity through enhancing glutamine metabolism.
CD8<sup>+</sup> T Cell-Derived Perforin Exacerbates Dysbiosis and Inflammatory Bowel Disease via β-Hydroxybutyrate Suppression in Mouse Colonic Epithelium.
Double-negative T cells in combination with ursodeoxycholic acid ameliorates immune-mediated cholangitis in mice.
IFITM1 aggravates ConA-Induced autoimmune hepatitis by promoting NKT cell activation through increased AMPK-Dependent mitochondrial function.
Regulatory TCRαβ<sup>+</sup> Double Negative T Cells Suppress γδ T Cells and Alleviate Colitis.
CD73 promotes the immunoregulatory functions of hepatic Tregs through enzymatic and nonenzymatic pathways in MASLD development.
Double-negative T cells ameliorate psoriasis by selectively inhibiting IL-17A-producing γδ<sup>low</sup> T cells.
Postoperative Ileus Murine Model.
Survival prediction in sigmoid colon cancer patients with liver metastasis: a prospective cohort study.
TCRαβ<sup>+</sup>NK1.1<sup>-</sup>CD4<sup>-</sup>CD8<sup>-</sup> double-negative T cells inhibit central and peripheral inflammation and ameliorate ischemic stroke in mice.
Resveratrol improves hepatic ischemia-reperfusion injury by inhibiting neutrophils via the ERK signaling pathway.
Rebalancing liver-infiltrating CCR3<sup>+</sup> and CD206<sup>+</sup> monocytes improves diet-induced NAFLD.
Inhibition of phospholipase D1 ameliorates hepatocyte steatosis and non-alcoholic fatty liver disease.
CCK2-receptor deficiency impairs immune balance by influencing CD4 <sup>+</sup> T cells development by inhibiting cortical-thymic-epithelial-cells