Area of research
Immunology · Oncology
Research interest
Research focused on Cell biology and Tumor microenvironment, with related work in Idiopathic pulmonary fibrosis, Gene knockdown, Moesin. Notable publications include 'A combination of humanised anti-CD19 and anti-BCMA CAR T cells in patients with relapsed or refractory multiple myeloma: a single-arm, phase 2 trial', 'Bidirectional regulation of neutrophil migration by mitogen-activated protein kinases', and 'Sphingosine-1-phosphate lyase is an endogenous suppressor of pulmonary fibrosis: role of S1P signalling and autophagy'.
Dual cytokine-engineered macrophages rejuvenate the tumor microenvironment and enhance anti-PD-1 therapy in renal cell carcinoma
CD70 as a target in cancer immunotherapy: advances, challenges, and future directions
CKS2 promotes the malignant phenotypes of bladder cancer cells via PI3K/AKT signaling pathway activation
Trans-2-decenal inhibits Phytophthora capsici by inducing ROS accumulation and mitochondrial dysfunction
Targeting a disintegrin and metalloprotease (ADAM) 17-CD122 axis enhances CD8+ T cell effector differentiation and anti-tumor immunity
Recombinant oncolytic adenovirus armed with CCL5, IL-12, and IFN-γ promotes CAR-T infiltration and proliferation in vivo to eradicate local and distal tumors
IL-21-armored B7H3 CAR-iNKT cells exert potent antitumor effects
Mitochondrial C1QBP is essential for T cell antitumor function by maintaining mitochondrial plasticity and metabolic fitness
Novel mesothelin-targeted chimeric antigen receptor-modified UNKT cells are highly effective in inhibiting tumor progression
Complement C1q binding protein regulates T cells’ mitochondrial fitness to affect their survival, proliferation, and anti–tumor immune function
P2X7R-NEK7-NLRP3 Inflammasome Activation: A Novel Therapeutic Pathway of Qishen Granule in the Treatment of Acute Myocardial Ischemia
ApoE/NOS3 Knockout Mice as a Novel Cardiovascular Disease Model of Hypertension and Atherosclerosis
Safety and efficacy of a humanized <scp>CD19</scp> chimeric antigen receptor T cells for relapsed/refractory acute lymphoblastic leukemia
Humanized <scp>CD19</scp>‐targeted chimeric antigen receptor <scp>T</scp> (<scp>CAR‐T</scp>) cells for relapsed/refractory pediatric acute lymphoblastic leukemia
Up-regulation of VANGL1 by IGF2BPs and miR-29b-3p attenuates the detrimental effect of irradiation on lung adenocarcinoma
A combination of humanised anti-CD19 and anti-BCMA CAR T cells in patients with relapsed or refractory multiple myeloma: a single-arm, phase 2 trial
Cell-in-Cell Phenomenon and Its Relationship With Tumor Microenvironment and Tumor Progression: A Review
Induction of entosis in prostate cancer cells by nintedanib and its therapeutic implications
Roles of Loss of Chromosome 14q Allele in the Prognosis of Renal Cell Carcinoma with C-reactive Protein Abnormity
Oxidant Sensing by TRPM2 Inhibits Neutrophil Migration and Mitigates Inflammation
Sphingosine-1-phosphate lyase is an endogenous suppressor of pulmonary fibrosis: role of S1P signalling and autophagy
Moesin and myosin phosphatase confine neutrophil orientation in a chemotactic gradient
Bidirectional regulation of neutrophil migration by mitogen-activated protein kinases
Early, nonciliary role for microtubule proteins in left–right patterning is conserved across kingdoms