Area of research
Molecular Biology
Research interest
Research interests include RNA and protein synthesis mechanisms, RNA modifications and cancer, DNA and Nucleic Acid Chemistry, and RNA Research and Splicing.
Quantitative CRACI reveals transcriptome-wide distribution of RNA dihydrouridine at base resolution
Nuclear 2′- <i>O</i> -methylation regulates RNA splicing through its binding protein FUBP1
GmSAUR46b Integrates Light Signals to Regulate Leaf Midrib Thickness and Stem Trichome Density in Soybean
KARR-seq reveals cellular higher-order RNA structures and RNA–RNA interactions
snoRNA-facilitated protein secretion revealed by transcriptome-wide snoRNA target identification
RNA interacts with topoisomerase I to adjust DNA topology
Building better mRNA for therapeutics
Targeting small GTPases: emerging grasps on previously untamable targets, pioneered by KRAS
Nm-Mut-seq: a base-resolution quantitative method for mapping transcriptome-wide 2′-O-methylation
HDAC6-G3BP2 promotes lysosomal-TSC2 and suppresses mTORC1 under ETV4 targeting-induced low-lactate stress in non-small cell lung cancer
Dynamic basis for dA•dGTP and dA•d8OGTP misincorporation via Hoogsteen base pairs
LIX1L promotes EMT and EGFR-TKIs resistance via nucleolin-mediated ribosomal RNA synthesis in NSCLC
A quantitative model predicts how m6A reshapes the kinetic landscape of nucleic acid hybridization and conformational transitions
ETV4 overexpression promotes progression of non–small cell lung cancer by upregulating PXN and MMP1 transcriptionally