Area of research
Neurology · Immunology
Research interest
Research interests include Neuroinflammation and Neurodegeneration Mechanisms, Intracerebral and Subarachnoid Hemorrhage Research, Immune cells in cancer, and Nicotinic Acetylcholine Receptors Study.
Reduction of neuronal activity mediated by blood-vessel regression in the adult brain
Autologous platelet rich gel in treatment of lower limb atherosclerotic occlusive disease in diabetic patients
Maternal circadian rhythm disruption affects neonatal inflammation via metabolic reprograming of myeloid cells
Microglia drive transient insult-induced brain injury by chemotactic recruitment of CD8+ T lymphocytes
Single-cell RNA sequencing deciphers the mechanism of sepsis-induced liver injury and the therapeutic effects of artesunate
Pregabalin mitigates microglial activation and neuronal injury by inhibiting HMGB1 signaling pathway in radiation-induced brain injury
Endothelial BACE1 Impairs Cerebral Small Vessels via Tight Junctions and eNOS
Inhibition of exosome release augments neuroinflammation following intracerebral hemorrhage
Neuroblast senescence in the aged brain augments natural killer cell cytotoxicity leading to impaired neurogenesis and cognition
Risk of COVID-19 infection in MS and neuromyelitis optica spectrum disorders
Depletion of microglia in developing cortical circuits reveals its critical role in glutamatergic synapse development, functional connectivity, and critical period plasticity
Cardiac arrest and resuscitation activates the hypothalamic-pituitary-adrenal axis and results in severe immunosuppression
Targeted role for sphingosine-1-phosphate receptor 1 in cerebrovascular integrity and inflammation during acute ischemic stroke
Inflammatory markers in Alzheimer’s disease and mild cognitive impairment: a meta-analysis and systematic review of 170 studies
Depletion of microglia augments the dopaminergic neurotoxicity of MPTP
Fingolimod enhances the efficacy of delayed alteplase administration in acute ischemic stroke by promoting anterograde reperfusion and retrograde collateral flow
Brain Ischemia Induces Diversified Neuroantigen-Specific T-Cell Responses That Exacerbate Brain Injury
Depletion of microglia exacerbates postischemic inflammation and brain injury
Brain Ischemia Suppresses Immunity in the Periphery and Brain via Different Neurogenic Innervations
Astrocyte-derived interleukin-15 exacerbates ischemic brain injury via propagation of cellular immunity
Neural stem cells sustain natural killer cells that dictate recovery from brain inflammation
Immune interventions in stroke
Ischemic neurons recruit natural killer cells that accelerate brain infarction
A Novel Nicotinic Mechanism Underlies β-Amyloid-Induced Neuronal Hyperexcitation
Human α4β2 Nicotinic Acetylcholine Receptor as a Novel Target of Oligomeric α-Synuclein