Area of research
Pulmonary and Respiratory Medicine · Cancer Research
Research interest
Research interests include Renal cell carcinoma treatment, Ferroptosis and cancer prognosis, Cancer, Hypoxia, and Metabolism, and Glioma Diagnosis and Treatment.
Stable isotope tracing in human plasma-like medium reveals metabolic and immune modulation of the glioblastoma microenvironment
Nitrogen metabolism profiling reveals cell state-specific pyrimidine synthesis pathway choice
TMOD-12. Preclinical and clinical assessment of chemoradiation after mutant IDH inhibitor treatment in IDH-mutant glioma
Advances in targeting histone deacetylase for treatment of solid tumors
Integrated multiomic profiling of breast cancer in the Chinese population reveals patient stratification and therapeutic vulnerabilities
Mutant IDH1 inhibition induces dsDNA sensing to activate tumor immunity
Metabolic inflexibility promotes mitochondrial health during liver regeneration
Ferroptosis heterogeneity in triple-negative breast cancer reveals an innovative immunotherapy combination strategy
De novo pyrimidine synthesis is a targetable vulnerability in IDH mutant glioma
Decreased Mitochondrial DNA Content Drives OXPHOS Dysregulation in Chromophobe Renal Cell Carcinoma
Nicotinamide mononucleotide adenylyltransferase uses its NAD+ substrate-binding site to chaperone phosphorylated Tau
Endocytosis-Mediated Replenishment of Amino Acids Favors Cancer Cell Proliferation and Survival in Chromophobe Renal Cell Carcinoma
Genomic and Transcriptomic Landscape of Triple-Negative Breast Cancers: Subtypes and Treatment Strategies
Mechanistic insights into NAD synthase NMNAT chaperoning phosphorylated Tau from pathological aggregation