Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include Cancer-related molecular mechanisms research, RNA modifications and cancer, Circular RNAs in diseases, and RNA Research and Splicing.
NEU1 sustains mitochondria-lysosome contacts to trigger lysosomal Cu2+/cathepsin escape and mitochondrial lysis in glioblastoma (NeuLysis)
circASAP1 induces renal clear cell carcinoma ferroptosis by binding to HNRNPC and thereby regulating GPX4
How growing up without siblings affects the adult brain and behaviour in the CHIMGEN cohort
Linagliptin synergizes with cPLA2 inhibition to enhance temozolomide efficacy by interrupting DPP4-mediated EGFR stabilization in glioma
Predictive Value of Residual SYNTAX Score II for Patients With Complex Coronary Disease and Chronic Renal Insufficiency After Percutaneous Coronary Intervention
mPPTMP195 nanoparticles enhance fracture recovery through HDAC4 nuclear translocation inhibition
Comparison of Fractional Flow Reserve and Resting Full-Cycle Ratio in the Functional Assessment of Coronary Artery Stenosis in Patients with Non-ST-Segment Elevation Acute Coronary Syndrome
Blockage of EGFR/AKT and mevalonate pathways synergize the antitumor effect of temozolomide by reprogramming energy metabolism in glioblastoma
Upregulated ribosome pathway plays a key role in HDAC4, improving the survival rate and biofunction of chondrocytes
Neuronal STAT3/HIF-1α/PTRF axis-mediated bioenergetic disturbance exacerbates cerebral ischemia-reperfusion injury via PLA2G4A.
PTRF/Cavin-1 enhances chemo-resistance and promotes temozolomide efflux through extracellular vesicles in glioblastoma
PTRF/Cavin-1 enhances chemo-resistance and promotes temozolomide efflux through extracellular vesicles in glioblastoma.
The Level of Histone Deacetylase 4 is Associated with Aging Cartilage Degeneration and Chondrocyte Hypertrophy
Inactivation of Ihh in Sp7-Expressing Cells Inhibits Osteoblast Proliferation, Differentiation, and Bone Formation, Resulting in a Dwarfism Phenotype with Severe Skeletal Dysplasia in Mice
The guiding value of hybrid resting full-cycle ratio and fractional flow reserve strategy for percutaneous coronary intervention in a Chinese real-world cohort with non-ST elevation acute coronary syndrome
1462 Adrenergic signaling augments cytotoxic T cell anti tumor activity in p53 deficient cancers by CXCL10 release
HOTAIR Up-Regulation Activates NF-κB to Induce Immunoescape in Gliomas
Single-Cell Transcriptomics of Glioblastoma Reveals a Unique Tumor Microenvironment and Potential Immunotherapeutic Target Against Tumor-Associated Macrophage
HOTAIR Up-Regulation Activates NF-κB to Induce Immunoescape in Gliomas.
Early administration of MPC-n(IVIg) selectively accumulates in ischemic areas to protect inflammation-induced brain damage from ischemic stroke.
Precise editing of FGFR3-TACC3 fusion genes with CRISPR-Cas13a in glioblastoma.
Sequence variant analysis reveals poor correlations in microbial taxonomic abundance between humans and mice after gnotobiotic transfer
EGFR‐vIII downregulated H2AZK4/7AC though the PI3K/AKT‐HDAC2 axis to regulate cell cycle progression
A Compound AC1Q3QWB Selectively Disrupts HOTAIR-Mediated Recruitment of PRC2 and Enhances Cancer Therapy of DZNep
Long non-coding RNA HOTAIR mediates the switching of histone H3 lysine 27 acetylation to methylation to promote epithelial-to-mesenchymal transition in gastric cancer.
A Compound AC1Q3QWB Selectively Disrupts HOTAIR-Mediated Recruitment of PRC2 and Enhances Cancer Therapy of DZNep.
Targeted design and identification of AC1NOD4Q to block activity of HOTAIR by abrogating the scaffold interaction with EZH2
Genome‐Wide CRISPR‐Cas9 Screening Identifies NF‐κB/E2F6 Responsible for EGFRvIII‐Associated Temozolomide Resistance in Glioblastoma
NanoRNP Overcomes Tumor Heterogeneity in Cancer Treatment
RUNX1 contributes to the mesenchymal subtype of glioblastoma in a TGFβ pathway-dependent manner.