Area of research
Molecular Biology · Artificial Intelligence
Research interest
Research interests include Bioinformatics and Genomic Networks, Single-cell and spatial transcriptomics, Plant tissue culture and regeneration, and Advanced Computational Techniques and Applications.
EPInformer: scalable and integrative prediction of gene expression from promoter-enhancer sequences with multimodal epigenomic profiles.
Defining and benchmarking open problems in single-cell analysis
Spatial multiomics decipher fibroblast–macrophage dynamics in systemic sclerosis
Defining and benchmarking open problems in single-cell analysis.
Spatial multiomics decipher fibroblast–macrophage dynamics in systemic sclerosis
Systematic benchmarking of computational methods to identify spatially variable genes.
Systematic benchmarking of computational methods to identify spatially variable genes
PHLOWER leverages single-cell multimodal data to infer complex, multi-branching cell differentiation trajectories.
Mapping spatially-resolved transcriptomes in systemic sclerosis
Single cell multi-omics of fibrotic kidney reveal epigenetic regulation of antioxidation and apoptosis within proximal tubule.
PHLOWER - Single cell trajectory analysis using Hodge Decomposition
scMEGA: single-cell multi-omic enhancer-based gene regulatory network inference.
RGT: a toolbox for the integrative analysis of high throughput regulatory genomics data.
A lncRNA identifies <i>Irf8</i> enhancer element in negative feedback control of dendritic cell differentiation.
RGT: a toolbox for the integrative analysis of high throughput regulatory genomics data
Spatial multi-omic map of human myocardial infarction
Spatial multi-omic map of human myocardial infarction.
Engineering circular RNA for enhanced protein production
Adult human kidney organoids originate from CD24<sup>+</sup> cells and represent an advanced model for adult polycystic kidney disease.
Retraction Note: Role of short-wavelength blue light in the formation of cataracts and the expression of caspase-1, caspase-11, Gasdermin D in rat lens epithelial cells: insights into a novel pathogenic mechanism of cataracts
MOJITOO: a fast and universal method for integration of multimodal single cell data
Chromatin-accessibility estimation from single-cell ATAC-seq data with scOpen.
Mutations and variants of ONECUT1 in diabetes
Mutations and variants of ONECUT1 in diabetes.
Transcriptional changes and the role of ONECUT1 in hPSC pancreatic differentiation.
Short-wavelength blue light contributes to the pyroptosis of human lens epithelial cells (hLECs)
RETRACTED ARTICLE: Role of Blueberry Anthocyanin Extract in the Expression of SIRT1 and NF-κB in Rat Lens Epithelial Cells in Experimentally Induced DM
Spatial multi-omic map of human myocardial infarction
The novel mutation P36R in LRP5L contributes to congenital membranous cataract via inhibition of laminin γ1 and c-MAF
Identification of transcription factor binding sites using ATAC-seq