Area of research
Molecular Biology · Plant Science
Research interest
Research interests include CRISPR and Genetic Engineering, Phytochemistry and Biological Activities, Natural product bioactivities and synthesis, and RNA and protein synthesis mechanisms.
Leveraging base excision repair for efficient adenine base editing of mitochondrial DNA.
Specific and efficient RNA A-to-I editing through cleavage of an ADAR inhibitor.
Clinical application of base editing for treating β-thalassaemia.
Precision Engineering for Ocular Gene Therapy: Molecular Tools, Delivery Platforms, and Disease Applications
Specific and efficient RNA A-to-I editing through cleavage of an ADAR inhibitor
IL-24 Is a Promising Molecular Adjuvant for Enhancing Protective Immunity Induced by DNA Vaccination Against Toxoplasma gondii
Proteomic analysis of premature umbilical cord blood and its relationship with bronchopulmonary dysplasia
Base editing of organellar DNA with programmable deaminases.
Integrating Multi-omics to Identify Age-Related Macular Degeneration Subtypes and Biomarkers
A cuproptosis-related prognostic signature for guiding clinical diagnosis and treatment in uveal melanoma patients
TLR4/TRIF/Caspase-8/Caspase-1 Pathway in Choroidal Endothelial Cells Promotes Choroidal Neovascularization
Base editing of organellar DNA with programmable deaminases
Base editing of the HBG promoter induces potent fetal hemoglobin expression with no detectable off-target mutations in human HSCs
Design and application of the transformer base editor in mammalian cells and mice.
Prime editor-mediated functional reshaping of <i>ACE2</i> prevents the entry of multiple human coronaviruses, including SARS-CoV-2 variants.
Highly efficient prime editing by introducing same-sense mutations in pegRNA or stabilizing its structure
Highly efficient prime editing by introducing same-sense mutations in pegRNA or stabilizing its structure.
Characterization, Hypoglycemic Activity, and Antioxidant Activity of Methanol Extracts From Amomum tsao-ko: in vitro and in vivo Studies
Prevalence of mitochondrial DNA mutations in sporadic patients with nonsyndromic sensorineural hearing loss
Eliminating base-editor-induced genome-wide and transcriptome-wide off-target mutations.
No observable guide-RNA-independent off-target mutation induced by prime editor
Camrelizumab versus investigator's choice of chemotherapy as second-line therapy for advanced or metastatic oesophageal squamous cell carcinoma (ESCORT): a multicentre, randomised, open-label, phase 3 study
Cas12a Base Editors Induce Efficient and Specific Editing with Low DNA Damage Response.
Simultaneous determination of 15 pesticide residues in Chinese cabbage and cucumber by liquid chromatography-tandem mass spectrometry utilizing online turbulent flow chromatography
<p>Risk Factors of Pulmonary Complications After Minimally Invasive Surgery for Elderly Patients with Vertebral Compression Fractures</p>
Efficient base editing in G/C-rich regions to model androgen insensitivity syndrome.
To BE or not to BE, that is the question.
Risk factors of pulmonary complications after minimally invasive surgery for elderly patients with vertebral compression fractures
Coding mutations in <i>NUS1</i> contribute to Parkinson’s disease
Identification of long noncoding RNAs in Schistosoma mansoni and Schistosoma japonicum