Area of research
Physiology · Epidemiology
Research interest
Research topics from publications: Telmisartan Improves Insulin Resistance: A Meta-Analysis; The correlation between serum asprosin and type 2 diabetic patients with obesity in the community; Association analysis between serum asprosin and metabolic characteristics, Complications in type 2 diabetic patients with different durations. Representative work: BACKGROUND: Diabetes mellitus, metabolic syndrome, and other obesity-related diseases are characterized by insulin resistance (IR) as a common pathophysiological change and are closely related to cardiovascular disease, which seriously threaten human health. Telmisartan belongs to a group of drugs called angiotensin II receptor antagonists (ARBs) and it can partially activate peroxisome proliferator-activated receptors. Animal experiments have confirmed that telmisartan can regulate glucose and lipid metabolism, and improve IR. STUDY QUESTION: This study performs a systematic review of the advantages of telmisartan in improving IR and compared it with other ARBs. STUDY DESIGN: Randomized con Aims: Asprosin is a newly discovered adipokine, it is associated with the insulin resistance, lipid metabolism disorder, diabetes and obesity. However, there have been no reports on the relationship between asprosin and type 2 diabetic patients with obesity. This study aims to investigate the relationship between serum asprosin and type 2 diabetic patients with obesity in the community. Materials and methods: A total of 491 patients with Type 2 Diabetes Mellitus (T2DM) were recruited from Zhuoma Community Care Station and Chengbei West Street Community Care Service Center in Changzhi City of Shanxi Province from November 2019 to July 2021. Patients were divided into the Normal group (n= 145)