Area of research
Molecular Biology · Geriatrics and Gerontology
Research interest
Research interests include Ubiquitin and proteasome pathways, Protein Degradation and Inhibitors, Sirtuins and Resveratrol in Medicine, and Peptidase Inhibition and Analysis.
Visualization of mitochondrial molecular dynamics during mitophagy process by label-free surface-enhanced Raman scattering spectroscopy
Targeted Protein Degradation by Electrophilic PROTACs that Stereoselectively and Site-Specifically Engage DCAF1
A Proteomic Approach Identifies Isoform-Specific and Nucleotide-Dependent RAS Interactions
High-Throughput Enzyme Assay for Screening Inhibitors of the ZDHHC3/7/20 Acyltransferases
Identification of putative muscarinic acetylcholine receptor genes in Bactrocera dorsalis and functional analysis of Bdor-mAChR-B
Olfactory Proteins and Their Expression Profiles in the Eucalyptus Pest Endoclita signifier Larvae
An Activity-Guided Map of Electrophile-Cysteine Interactions in Primary Human T Cells
NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle
HDAC11 regulates type I interferon signaling through defatty-acylation of SHMT2
Loss of Sirtuin 1 Alters the Secretome of Breast Cancer Cells by Impairing Lysosomal Integrity
A Small‐Molecule SIRT2 Inhibitor That Promotes K‐Ras4a Lysine Fatty‐Acylation
SIRT2 and Lysine Fatty Acylation Regulate the Activity of RalB and Cell Migration
Protein Lipidation: Occurrence, Mechanisms, Biological Functions, and Enabling Technologies
Direct Comparison of SIRT2 Inhibitors: Potency, Specificity, Activity‐Dependent Inhibition, and On‐Target Anticancer Activities
HPLC-Based Enzyme Assays for Sirtuins
SIRT2 and lysine fatty acylation regulate the transforming activity of K-Ras4a
SIRT6 regulates Ras-related protein R-Ras2 by lysine defatty-acylation
Differentiating physicochemical properties between NDRIs and sNRIs clinically important for the treatment of ADHD
Comparative Nucleotide-Dependent Interactome Analysis Reveals Shared and Differential Properties of KRas4a and KRas4b
Identifying the functional contribution of the defatty-acylase activity of SIRT6
SIRT7 Is Activated by DNA and Deacetylates Histone H3 in the Chromatin Context
SIRT2 Reverses 4-Oxononanoyl Lysine Modification on Histones
Lysine fatty acylation promotes lysosomal targeting of TNF-α
RET Site: Training STEM teachers in alternative (biomass, solar, wind, and hydrogen) energy research through hands on laboratory and computational experiences
REU Site: Training Undergraduates in Electrochemical Technologies for Clean Fuels (Biofuels and Hydrogen) Production and Applications
The Mechanism and Function of SDG2 in Regulating Chromatin Structure and Gene Expression