Area of research
Biomaterials · Biomedical Engineering
Research interest
Research interests include Nanoparticle-Based Drug Delivery, Nanoplatforms for cancer theranostics, MicroRNA in disease regulation, and RNA Interference and Gene Delivery.
Microbial metabolism dysfunction induced by transarterial chemoembolization aggravates postprocedural liver injury in HCC
A nanodrug provokes antitumor immune responses via synchronous multicellular regulation for enhanced cancer immunotherapy
Adrenomedullin Inhibits the Efficacy of Combined Immunotherapy and Targeted Therapy in Biliary Tract Cancer by Disrupting Endothelial Cell Functions
A polymeric nanovesicle delivers sulfopin and gemcitabine to remodel tumor microenvironment for enhanced chemoimmunotherapy against orthotopic pancreatic cancer
High Trop-2 expression in pulmonary sarcomatoid carcinoma reveals antibody–drug conjugate targeting Trop-2 is a promising therapeutic approach
Anti-inflammatory effect of lignans from flaxseed after fermentation by lactiplantibacillus plantarum SCB0151 in vitro
Reduction-sensitive polymeric carrier for the targeted delivery of a quinazoline derivative for enhanced generation of reactive oxygen species against cancer.
Nanodrug enhances post-ablation immunotherapy of hepatocellular carcinoma via promoting dendritic cell maturation and antigen presentation.
Nanodrug removes physical barrier to promote T-cell infiltration for enhanced cancer immunotherapy
Sono-promoted drug penetration and extracellular matrix modulation potentiate sonodynamic therapy of pancreatic ductal adenocarcinoma
A nanodrug simultaneously inhibits pancreatic stellate cell activation and regulatory T cell infiltration to promote the immunotherapy of pancreatic cancer
Retinol-binding protein-hijacking nanopolyplex delivering siRNA to cytoplasm of hepatic stellate cell for liver fibrosis alleviation.
Nanodrug removes physical barrier to promote T-cell infiltration for enhanced cancer immunotherapy.
T cell-mediated targeted delivery of tadalafil regulates immunosuppression and polyamine metabolism to overcome immune checkpoint blockade resistance in hepatocellular carcinoma
T cell-mediated targeted delivery of tadalafil regulates immunosuppression and polyamine metabolism to overcome immune checkpoint blockade resistance in hepatocellular carcinoma.
PEG-Sheddable Nanodrug Remodels Tumor Microenvironment to Promote Effector T Cell Infiltration and Revise Their Exhaustion for Breast Cancer Immunotherapy.
A nanodrug simultaneously inhibits pancreatic stellate cell activation and regulatory T cell infiltration to promote the immunotherapy of pancreatic cancer.
Neutrophil Extracellular Traps (NETs) Promote Non-Small Cell Lung Cancer Metastasis by Suppressing lncRNA MIR503HG to Activate the NF-κB/NLRP3 Inflammasome Pathway
Nanodrug enhances post-ablation immunotherapy of hepatocellular carcinoma via promoting dendritic cell maturation and antigen presentation
The efficacy and safety analysis of first-line immune checkpoint inhibitors in pulmonary sarcomatoid carcinoma
rhG-CSF is associated with an increased risk of metastasis in NSCLC patients following postoperative chemotherapy
Pertuzumab and trastuzumab for HER2-positive, metastatic biliary tract cancer (MyPathway): a multicentre, open-label, phase 2a, multiple basket study
Nanodrug with dual-sensitivity to tumor microenvironment for immuno-sonodynamic anti-cancer therapy
Nanodrug with dual-sensitivity to tumor microenvironment for immuno-sonodynamic anti-cancer therapy.
Multifunctional Nanodrug Mediates Synergistic Photodynamic Therapy and MDSCs‐Targeting Immunotherapy of Colon Cancer
Nanomedicine Directs Neuronal Differentiation of Neural Stem Cells via Silencing Long Noncoding RNA for Stroke Therapy
Dual-Sensitive PEG-Sheddable Nanodrug Hierarchically Incorporating PD-L1 Antibody and Zinc Phthalocyanine for Improved Immuno-Photodynamic Therapy
Core-shell lipoplexes inducing active macropinocytosis promote intranasal delivery of c-Myc siRNA for treatment of glioblastoma
Nanomedicine Directs Neuronal Differentiation of Neural Stem Cells via Silencing Long Noncoding RNA for Stroke Therapy.
A photo and tumor microenvironment activated nano-enzyme with enhanced ROS generation and hypoxia relief for efficient cancer therapy.
EFRI E3P: A novel sequential catalytic solvolysis process for deconstructing municipal waste plastics
I-Corps: Development of Bent DNA Molecules as Amplifying Sensors
IIBR Instrumentation: Collaborative Research: Development of a Single-Biomolecule Detection Instrument via Digital Counting of Nanoparticles
Understanding the antimicrobial mechanism of metal nanoparticles using super resolution fluorescence microscopy
Growth of Hybrid Polymeric Nanostructures for Enzyme-Free Amplified Protein Imaging
CAREER: Creation of Complex Biomimetic Materials via Molecular Recognition
INSPIRE: Programming Materials via Biomolecular Engineering
Reversible Cell Capture and Release for Cell Separation
MRI: Acquisition of Equipment to Establish Mobile Testing Infrastructure for Bring Your Own Device Research and Education
Controlling Protein Release via Intermolecular Hybridization
RET Site in Cyber Security
INSPIRE: Programming Materials via Biomolecular Engineering
MRI: Acquisition of an Online Banking System for Information Assurance Research
REU Site in China: Ecological and Environmental Research in Urbanized Landscape
Controlling Protein Release via Intermolecular Hybridization
Reversible Cell Capture and Release for Cell Separation
CAREER: Creation of Complex Biomimetic Materials via Molecular Recognition
Multivalent "Artificial Antibody" Based on RNA/Dendrimer-Like Star Polymer Hybrid Nanomaterials
REU Site: Research Experience in Environmental and Natural Resource Sciences