Area of research
Immunology · Infectious Diseases
Research interest
Research interests include Immunodeficiency and Autoimmune Disorders, T-cell and B-cell Immunology, COVID-19 Clinical Research Studies, and Immune Cell Function and Interaction.
Germline mutations in a G protein identify signaling cross-talk in T cells
GIMAP5 deficiency reveals a mammalian ceramide-driven longevity assurance pathway
Correction: Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19
Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19
Interfering with Interferons: A Critical Mechanism for Critical COVID-19 Pneumonia
Additional file 2 of Rare predicted loss-of-function variants of type I IFN immunity genes are associated with life-threatening COVID-19
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies
Inborn errors of OAS–RNase L in SARS-CoV-2–related multisystem inflammatory syndrome in children
Genetic regulation of OAS1 nonsense-mediated decay underlies association with COVID-19 hospitalization in patients of European and African ancestries
Vaccine breakthrough hypoxemic COVID-19 pneumonia in patients with auto-Abs neutralizing type I IFNs
<i>DDX58</i> Is Associated With Susceptibility to Severe Influenza Virus Infection in Children and Adolescents
Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths
Biochemically deleterious human <i>NFKB1</i> variants underlie an autosomal dominant form of common variable immunodeficiency
IFIH1 loss-of-function variants contribute to very early-onset inflammatory bowel disease
Genetic regulation of <i>OAS1</i> nonsense-mediated decay underlies association with risk of severe COVID-19
Autoantibodies against type I IFNs in patients with life-threatening COVID-19
Inborn errors of type I IFN immunity in patients with life-threatening COVID-19
Extended clinical and immunological phenotype and transplant outcome in CD27 and CD70 deficiency
BACH2 immunodeficiency illustrates an association between super-enhancers and haploinsufficiency
Recurrent rhinovirus infections in a child with inherited MDA5 deficiency
Elevated basal serum tryptase identifies a multisystem disorder associated with increased TPSAB1 copy number
Combined immunodeficiency and Epstein-Barr virus–induced B cell malignancy in humans with inherited CD70 deficiency
Patients with LRBA deficiency show CTLA4 loss and immune dysregulation responsive to abatacept therapy
Immune dysregulation in human subjects with heterozygous germline mutations in <i>CTLA4</i>
Early-onset lymphoproliferation and autoimmunity caused by germline STAT3 gain-of-function mutations
Somatic reversion in dedicator of cytokinesis 8 immunodeficiency modulates disease phenotype
Identification of Patients with RAG Mutations Previously Diagnosed with Common Variable Immunodeficiency Disorders
Four lysozymes (one c-type and three g-type) in catfish are drastically but differentially induced after bacterial infection