Area of research
Immunology · Oncology
Research interest
Research interests include Cancer Immunotherapy and Biomarkers, Immune cells in cancer, Phagocytosis and Immune Regulation, and CAR-T cell therapy research.
Cancer immunology data engine reveals secreted AOAH as a potential immunotherapy
Extra-skeletal Ewing’s sarcoma with EWSR1::ERG translocation of the breast: a case report
FASN Inhibition Decreases MHC-I Degradation and Synergizes with PD-L1 Checkpoint Blockade in Hepatocellular Carcinoma
Estimation of cell lineages in tumors from spatial transcriptomics data
Nasopharyngeal carcinoma cells promote regulatory T cell development and suppressive activity via CD70-CD27 interaction
Enhanced mitophagy driven by ADAR1-GLI1 editing supports the self-renewal of cancer stem cells in HCC
A T cell resilience model associated with response to immunotherapy in multiple tumor types
Targeting TROY-mediated P85a/AKT/TBX3 signaling attenuates tumor stemness and elevates treatment response in hepatocellular carcinoma
Systematic investigation of cytokine signaling activity at the tissue and single-cell levels
Comprehensive single-cell sequencing reveals the stromal dynamics and tumor-specific characteristics in the microenvironment of nasopharyngeal carcinoma
Elevated expression of RIT1 hyperactivates RAS/MAPK signal and sensitizes hepatocellular carcinoma to combined treatment with sorafenib and AKT inhibitor
FOXO1 promotes tumor progression by increased M2 macrophage infiltration in esophageal squamous cell carcinoma
C-terminal truncated HBx initiates hepatocarcinogenesis by downregulating TXNIP and reprogramming glucose metabolism
A hepatocyte differentiation model reveals two subtypes of liver cancer with different oncofetal properties and therapeutic targets
Recurrent ZNF83-E293V Mutation Promotes Bladder Cancer Progression through the NF-κB Pathway via Transcriptional Dysregulation of S100A8
ZIC2 is downregulated and represses tumor growth <i>via</i> the regulation of STAT3 in breast cancer
Role of YAP-related T cell imbalance and epidermal keratinocyte dysfunction in the pathogenesis of atopic dermatitis
QUBIC2: a novel and robust biclustering algorithm for analyses and interpretation of large-scale RNA-Seq data
<i>ANGPTL1</i> Interacts with Integrin α1β1 to Suppress HCC Angiogenesis and Metastasis by Inhibiting JAK2/STAT3 Signaling