Area of research
Cellular and Molecular Neuroscience · Molecular Biology
Research interest
Research focused on Neuroscience and Hippocampal formation, with related work in Long-term potentiation, Synaptic plasticity, Hippocampus. Notable publications include 'Loss of ferroportin induces memory impairment by promoting ferroptosis in Alzheimer’s disease', 'Antidepressant‐like effects of ginsenoside Rg1 are due to activation of the BDNF signalling pathway and neurogenesis in the hippocampus', and 'A Novel MicroRNA-124/PTPN1 Signal Pathway Mediates Synaptic and Memory Deficits in Alzheimer’s Disease'.
Epigenetic mechanisms in depression: Implications for pathogenesis and treatment
Correction: Loss of ferroportin induces memory impairment by promoting ferroptosis in Alzheimer’s disease
Gut microbiome-derived ammonia modulates stress vulnerability in the host
Mitochondrial fission drives neuronal metabolic burden to promote stress susceptibility in male mice
BNIP3L/NIX-mediated mitophagy alleviates passive stress-coping behaviors induced by tumor necrosis factor-α
PDGF‐BB‐Dependent Neurogenesis Buffers Depressive‐Like Behaviors by Inhibition of GABAergic Projection from Medial Septum to Dentate Gyrus
CD200 in dentate gyrus improves depressive-like behaviors of mice through enhancing hippocampal neurogenesis via alleviation of microglia hyperactivation
Cell type-specific NRBF2 orchestrates autophagic flux and adult hippocampal neurogenesis in chronic stress-induced depression
Enhanced TARP-γ8-PSD-95 coupling in excitatory neurons contributes to the rapid antidepressant-like action of ketamine in male mice
Prime editing-mediated correction of the CFTR W1282X mutation in iPSCs and derived airway epithelial cells
α-MSH-catabolic enzyme prolylcarboxypeptidase in nucleus accumbens shell ameliorates stress susceptibility in mice through regulating synaptic plasticity
Nrf2: An all-rounder in depression
Repetitive transcranial magnetic stimulation exerts anti-inflammatory effects via modulating glial activation in mice with chronic unpredictable mild stress-induced depression
Long noncoding RNA Gm2694 drives depressive-like behaviors in male mice by interacting with GRP78 to disrupt endoplasmic reticulum homeostasis
SVCT2–mediated ascorbic acid uptake buffers stress responses via DNA hydroxymethylation reprogramming of S100 calcium-binding protein A4 gene
Loss of ferroportin induces memory impairment by promoting ferroptosis in Alzheimer’s disease
miR-135a-5p mediates memory and synaptic impairments via the Rock2/Adducin1 signaling pathway in a mouse model of Alzheimer’s disease
Erasing m6A-dependent transcription signature of stress-sensitive genes triggers antidepressant actions
N-acetylcysteine facilitates extinction of cued fear memory in rats via reestablishing basolateral amygdala glutathione homeostasis
Transcription Factor TWIST1 Integrates Dendritic Remodeling and Chronic Stress to Promote Depressive-like Behaviors
Hippocampal CD39/ENTPD1 promotes mouse depression‐like behavior through hydrolyzing extracellular ATP
A novel pathway regulates social hierarchy via lncRNA AtLAS and postsynaptic synapsin IIb
Angiotensin-Converting Enzyme Inhibitor Rapidly Ameliorates Depressive-Type Behaviors via Bradykinin-Dependent Activation of Mammalian Target of Rapamycin Complex 1
Targeting redox-altered plasticity to reactivate synaptic function: A novel therapeutic strategy for cognitive disorder
Activation of EphB2 in the basolateral amygdala promotes stress vulnerability of mice by increasing NMDA-dependent synaptic function
Activation of AMPK‐dependent autophagy in the nucleus accumbens opposes cocaine‐induced behaviors of mice
MicroRNA-26a/Death-Associated Protein Kinase 1 Signaling Induces Synucleinopathy and Dopaminergic Neuron Degeneration in Parkinson’s Disease
Metformin produces anxiolytic‐like effects in rats by facilitating <scp>GABA<sub>A</sub></scp> receptor trafficking to membrane
miR-214-3p Targets β-Catenin to Regulate Depressive-like Behaviors Induced by Chronic Social Defeat Stress in Mice
SAR405, a Highly Specific VPS34 Inhibitor, Disrupts Auditory Fear Memory Consolidation of Mice via Facilitation of Inhibitory Neurotransmission in Basolateral Amygdala