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Jie Zhang

Merck & Co., Inc., Rahway, NJ, USA (United States) · US
Area of research
Molecular Biology · Infectious Diseases
Research interest
Research interests include SARS-CoV-2 and COVID-19 Research, COVID-19 Clinical Research Studies, Glutathione Transferases and Polymorphisms, and Genomics, phytochemicals, and oxidative stress.
h-index
47
citations
7,924
works
307
NIH funding
primary concept
email

Recent publications

Small Molecule Inhibition of VDAC1 Reroutes Mitochondrial Metabolite Flux
Molecules and Cells 2026cited by 0position: contributordoi
REDOX Imbalance and Oxidative Stress in the Intervertebral Disc: The Effect of Mechanical Stress and Cigarette Smoking on ER Stress and Mitochondrial Dysfunction.
2025cited by 9position: contributordoi
Randomized, double-blind, phase III LEAP-003 study of first-line lenvatinib plus pembrolizumab versus placebo plus pembrolizumab for unresectable or metastatic melanoma
Annals of Oncology 2025cited by 5position: middledoi
Metabolic engineering of Clostridium tyrobutyricum for hexanoic acid and hexanol production
SSRN Electronic Journal 2025cited by 0position: middledoi
miR-214-3p promotes the pathogenesis of Parkinson's disease by inhibiting autophagy
Biomedicine & Pharmacotherapy 2024cited by 18position: contributordoi
Oral administration of ovalbumin ameliorates specific food allergy via inhibiting gasdermin C-mediated pyroptosis and regulating microbial homeostasis
Food Bioscience 2024cited by 16position: middledoi
C. difficile intoxicates neurons and pericytes to drive neurogenic inflammation
Nature 2023cited by 56position: middledoi
Microsomal glutathione transferase 1 in cancer and the regulation of ferroptosis
Advances in cancer research 2023cited by 22position: firstdoi
A role for microsomal glutathione transferase 1 in melanin biosynthesis and melanoma progression
Journal of Biological Chemistry 2023cited by 7position: contributordoi
Respiratory and Cardiometabolic Comorbidities and Stages I to III NSCLC Survival: A Pooled Analysis From the International Lung Cancer Consortium
Journal of Thoracic Oncology 2022cited by 26position: middledoi
Accounting for <i>EGFR</i> Mutations in Epidemiologic Analyses of Non–Small Cell Lung Cancers: Examples Based on the International Lung Cancer Consortium Data
Cancer Epidemiology Biomarkers & Prevention 2022cited by 2position: middledoi
Structural basis for CSPG4 as a receptor for TcdB and a therapeutic target in Clostridioides difficile infection
Nature Communications 2021cited by 72position: middledoi
Nuclear PFKP promotes CXCR4-dependent infiltration by T cell acute lymphoblastic leukemia
Journal of Clinical Investigation 2021cited by 38position: contributordoi
Development of Telintra as an Inhibitor of Glutathione S-Transferase P.
2021cited by 15position: contributordoi
Glutathione &lt;i&gt;S&lt;/i&gt;-Transferase P Influences Redox Homeostasis and Response to Drugs that Induce the Unfolded Protein Response in Zebrafish.
2021cited by 2position: contributordoi
SARS-CoV-2 neutralizing antibody levels are correlated with severity of COVID-19 pneumonia.
2020cited by 49position: contributordoi
Altered redox regulation and S-glutathionylation of BiP contribute to bortezomib resistance in multiple myeloma.
2020cited by 36position: contributordoi
Retrograde signaling by a mtDNA-encoded non-coding RNA preserves mitochondrial bioenergetics.
2020cited by 25position: contributordoi
Mitochondrial Function in Enamel Development.
2020cited by 9position: contributordoi
Author Correction: 3-ketodihydrosphingosine reductase mutation induces steatosis and hepatic injury in zebrafish.
2020cited by 2position: contributordoi
Sulfated glycosaminoglycans and low-density lipoprotein receptor contribute to Clostridium difficile toxin A entry into cells
Nature Microbiology 2019cited by 105position: middledoi
Isoflavone ME-344 Disrupts Redox Homeostasis and Mitochondrial Function by Targeting Heme Oxygenase 1.
2019cited by 31position: contributordoi
3-ketodihydrosphingosine reductase mutation induces steatosis and hepatic injury in zebrafish.
2019cited by 23position: contributordoi
Pharmacology of ME-344, a novel cytotoxic isoflavone.
2019cited by 22position: contributordoi
Eupalinolide J Suppresses the Growth of Triple-Negative Breast Cancer Cells &lt;i&gt;via&lt;/i&gt; Targeting STAT3 Signaling Pathway.
2019cited by 20position: contributordoi
Palmitic Acid-Enriched Diet Induces Hepatic Steatosis and Injury in Adult Zebrafish.
2019cited by 19position: contributordoi
Endoplasmic Reticulum Protein Disulfide Isomerase Shapes T Cell Efficacy for Adoptive Cellular Therapy of Tumors.
2019cited by 17position: contributordoi
Racial disparities, cancer and response to oxidative stress.
2019cited by 12position: contributordoi
A seleno-hormetine protects bone marrow hematopoietic cells against ionizing radiation-induced toxicities.
2019cited by 12position: contributordoi
S-Glutathionylated Serine Proteinase Inhibitors as Biomarkers for Radiation Exposure in Prostate Cancer Patients.
2019cited by 8position: contributordoi

Grants

A Team-Based Model for Co-Adapting Existing Middle-School Science Curricula for Culturally and Linguistically Diverse Learners
NSF2247435$2,068,3062023–2027PIRePORTER
Doctoral Dissertation Research: The Representation and Processing of Vowel Contrasts
NSF2314478$18,3542023–2024PIRePORTER
EAGER: Collaborative Research:Blockchain Graphs as Testbeds of Power Grid Resilience and Functionality Metrics
NSF2039701$186,7292020–2024PIRePORTER
Travel Support for Hinode-14/IRIS-11 Joint Science Meeting
NSF2025986$18,7522020–2022PIRePORTER
Neural mechanisms for phonological alternation with high and low productivity - a case study on tone sandhi
NSF1826547$439,7702018–2024PIRePORTER
EAGER: Collaborative Research: Local Topological Properties of Power Flow Networks, and Their Role in Power System Functionality
NSF1824716$154,1052018–2022PIRePORTER
Collaborative Research: SHINE: Data-constrained Simulations of Coronal Mass Ejection Initiation and Propagation
NSF1460188$162,5282015–2018PIRePORTER
SHINE: Study the Evolution of Coronal Mass Ejections from the Sun to the Earth
NSF1156120$338,6562012–2015PIRePORTER
CAREER: Comprehensive Study of Initiation and Evolution of Solar Energetic Phenomena
NSF0748003$468,4982008–2014PIRePORTER
Testing the Productivity of Chinese Tone Sandhi
NSF0750773$300,0002008–2013PIRePORTER
SHINE: Understanding Characteristics of Coronal Mass Ejections (CMEs)
NSF0454613$333,4232005–2008PIRePORTER
A Study on Origin of Coronal Mass Ejections
NSF0203226$113,7252002–2004PIRePORTER

Frequent collaborators

· 6 papers (2020–2026)Ralf Gerhard · Medizinische Hochschule Hannover4 papers (2016–2023)Min Dong · Boston Children's Hospital4 papers (2016–2023)Liang Tao · East China University of Science and Technology3 papers (2016–2021)Zhiwei Ye · Medical University of South Carolina2 papers (2025–2026)A. Blumental-Perry · Jacobs (United States)2 papers (2020–2020) · 2 papers (2019–2021)David T. Breault · Harvard Stem Cell Institute2 papers (2016–2019)Kenneth D. Tew · MUSC Hollings Cancer Center2 papers (2021–2023)Julian G. Hurdle · Texas A&M University2 papers (2016–2023) · 2 papers (2021–2023)Wei Chen · Southeast University2 papers (2020–2020)Zhiwei Chen · Nanchang University1 papers (2018–2018)Shuangshuang Xu · Shandong University of Technology1 papers (2015–2015)Jun Guo · Hebei Medical University1 papers (2025–2025)Mei Dong · University of Toronto1 papers (2022–2022)Xin Liu · Union Hospital1 papers (2013–2013)Hongbing Chen · Deutsches Historisches Institut Washington1 papers (2024–2024)Geoffrey Liu · Yunnan Institute of Tropical Crops1 papers (2022–2022)Weiqi Li · Guangdong University of Technology1 papers (2017–2017)