Area of research
Molecular Biology · Epidemiology
Research interest
Research interests include Liver Disease Diagnosis and Treatment, MicroRNA in disease regulation, Immune Cell Function and Interaction, and Glycosylation and Glycoproteins Research.
Platelet activation plays a pro-inflammatory role in myasthenia gravis
Precision treatment in advanced hepatocellular carcinoma
PDIA3 orchestrates effector T cell program by serving as a chaperone to facilitate the non-canonical nuclear import of STAT1 and PKM2
Shorter telomere length increases the risk of lymphocyte immunodeficiency: A Mendelian randomization study.
The effect of liver metastases on clinical efficacy of <scp>first‐line</scp> programmed death‐1 inhibitor plus chemotherapy in esophageal squamous cell carcinoma: A post hoc analysis of <scp>ASTRUM</scp>‐007 and <scp>meta‐analysis</scp>
Potential role of SNP rs2071475 in rheumatoid arthritis and inflammatory bowel disease in the East Asian population: a Mendelian randomization study.
Safety and efficacy results from the phase I/IIa study of FG-M108 plus CAPOX as first-line (1L) treatment for patients with CLDN18.2+/HER2- locally advanced unresectable or metastatic gastric or gastroesophageal junction (G/GEJ) adenocarcinoma.
Shorter telomere length increases the risk of lymphocyte immunodeficiency: A Mendelian randomization study
Camrelizumab plus rivoceranib versus sorafenib as first-line therapy for unresectable hepatocellular carcinoma (CARES-310): a randomised, open-label, international phase 3 study
First-line serplulimab or placebo plus chemotherapy in PD-L1-positive esophageal squamous cell carcinoma: a randomized, double-blind phase 3 trial
Pharmaco-proteogenomic characterization of liver cancer organoids for precision oncology
Ubc9 regulates the expression of MHC II in dendritic cells to enhance DSS-induced colitis by mediating RBPJ SUMOylation
Pucotenlimab in patients with advanced mismatch repair-deficient or microsatellite instability-high solid tumors: A multicenter phase 2 study
Updated results of first-line serplulimab versus placebo plus chemotherapy in PD-L1–positive esophageal squamous cell carcinoma: A randomized, double-blind, multicenter phase 3 study (ASTRUM-007).
Changing epidemiology of hepatocellular carcinoma in Asia
Single-cell transcriptomic analysis suggests two molecularly distinct subtypes of intrahepatic cholangiocarcinoma
Multimodule characterization of immune subgroups in intrahepatic cholangiocarcinoma reveals distinct therapeutic vulnerabilities
Neoadjuvant cabozantinib and nivolumab convert locally advanced hepatocellular carcinoma into resectable disease with enhanced antitumor immunity
A global systematic review and meta-analysis on laparoscopic vs open right hemicolectomy with complete mesocolic excision
Efficacy of HX008 in high microsatellite instability/mismatch repair–defificient (MSI-H/dMMR) solid tumors: Results from a multicenter phase II open-label study.
Global immune characterization of HBV/HCV-related hepatocellular carcinoma identifies macrophage and T-cell subsets associated with disease progression
Autoantibody signature in hepatocellular carcinoma using seromics
Identification of critical radioresistance genes in esophageal squamous cell carcinoma by whole-exome sequencing
Atorvastatin combined with dexamethasone in chronic subdural haematoma (ATOCH II): study protocol for a randomised controlled trial
Heterogeneous immunogenomic features and distinct escape mechanisms in multifocal hepatocellular carcinoma
Activated and Exhausted MAIT Cells Foster Disease Progression and Indicate Poor Outcome in Hepatocellular Carcinoma
High kinesin family member 11 expression predicts poor prognosis in patients with clear cell renal cell carcinoma
High Expression of LTBP2 Contributes to Poor Prognosis in Colorectal Cancer Patients and Correlates with the Mesenchymal Colorectal Cancer Subtype
Effect and Safety of Meropenem–Vaborbactam versus Best-Available Therapy in Patients with Carbapenem-Resistant Enterobacteriaceae Infections: The TANGO II Randomized Clinical Trial
Analysis of mulberry leaf components in the treatment of diabetes using network pharmacology