Area of research
Management, Monitoring, Policy and Law · Ecology
Research interest
Research topics from publications: Cold stress induces colitis-like phenotypes in mice by altering gut microbiota and metabolites. Representative work: Introduction: The modernized lifestyle has been paralleled by an epidemic of inflammatory bowel disease (IBD). Excessive consumption of cold beverages is especially common among the modern humans. However, whether cold stress contributes directly to the gut barrier and gut-brain axis is not clear. Methods: We conducted a cold stress model induced by cold water. The mice were treated with 14 consecutive days of intragastric cold or common water administration. We observed changes in gut transit and gut barrier in the colon. We also employed RNA sequencing-based transcriptomic analysis to identify the genes potentially driving gut injury, and simultaneously examined the gut microbiota and meta