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Yingjian Hao

Nanjing Tech University · CN
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Area of research
Oceanography · Mechanics of Materials
Research interest
Research topics from publications: Engineered inhaled nanocatalytic therapy for ischemic cerebrovascular disease by inducing autophagy of abnormal mitochondria; Study on the Dynamic Characteristics of the Impact Loads in a Near-Wall Double-Cavitation Bubble Collapse. Representative work: Abstract Mitochondrial dysfunction and subsequent accumulation of reactive oxygen species (ROS) are key contributors to the pathology of ischemic cerebrovascular disease. Therefore, elimination of ROS and damaged mitochondria is crucial for the effective treatment of this disease. For this purpose, we designed an inhalation nanotherapeutic agent, P/D@Mn/Co 3 O 4 , to treat ischemic cerebrovascular disease. Mn/Co 3 O 4 effectively removed excess ROS from cells, reduced acute cellular oxidative stress, and protected neural cells from apoptosis. Furthermore, it depleted the H + surrounding mitochondria and depolarized the mitochondrial membrane potential, inducing mitophagy and eliminating abno Cavitation and cavitation erosion are complex hydrodynamic behaviors that significantly influence the stability and reliability of pumping units in aerospace and navigation power systems, hydraulic engineering, and other fields. Studies on cavitation have primarily and heavily focused on the collapse of multiple cavitation bubbles; understanding the movement of multiple cavitation bubbles is important for cavitation research. In this study, the collapse process of near-wall double-cavitation bubbles was numerically simulated and experimentally verified, and the evolution of the near-wall double-cavitation bubble collapse was investigated. Two different distances were altered in the study. Th
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Recent publications

Engineered inhaled nanocatalytic therapy for ischemic cerebrovascular disease by inducing autophagy of abnormal mitochondria
npj Regenerative Medicine 2023cited by 17position: middledoi
Study on the Dynamic Characteristics of the Impact Loads in a Near-Wall Double-Cavitation Bubble Collapse
Processes 2023cited by 7position: middledoi

Grants

No grants ingested yet.

Frequent collaborators

· 1 papers (2023–2023) · 1 papers (2023–2023) · 1 papers (2023–2023)Zhenye Gu · Jiangsu University1 papers (2023–2023)Ji-Min Cao · Shanxi Medical University1 papers (2023–2023)Bin Zheng · Jilin University1 papers (2023–2023)Shuchao Wang · Tianjin University1 papers (2023–2023)Wei Han · Ministry of Education of the People's Republic of China1 papers (2023–2023)Wangxu Li · Xihua University1 papers (2023–2023)Deping Wang · University of California, Davis1 papers (2023–2023)Xin Zhou · Nanjing Tech University1 papers (2023–2023)Bowen Li · Anhui Medical University1 papers (2023–2023)Hua Wang · Xinxiang Central Hospital1 papers (2023–2023)
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