Area of research
Epidemiology · Neurology
Research interest
Research focused on Autophagy and TFEB, with related work in Genetically modified mouse, Mutant, Disease. Notable publications include 'Allele-selective lowering of mutant HTT protein by HTT–LC3 linker compounds', 'Balancing mTOR Signaling and Autophagy in the Treatment of Parkinson’s Disease', and 'Degradation of lipid droplets by chimeric autophagy-tethering compounds'.
Quantitative evaluation of radiation-induced heart disease in beagle dogs by speckle tracking echocardiography
α-Synuclein amyloid fibril directly binds to LC3B and suppresses SQSTM1/p62-mediated selective autophagy
P53 upregulation by USP7-engaging molecular glues
Quantitative evaluation of radiation-induced heart disease in patients with lung cancer: a three-dimensional speckle tracking imaging study
S1PR1 regulates ovarian cancer cell senescence through the PDK1-LATS1/2-YAP pathway
β-arrestin2 deficiency ameliorates S-100-induced autoimmune hepatitis in mice by inhibiting infiltration of monocyte-derived macrophage and attenuating hepatocyte apoptosis
Corrigendum to “Traditional Chinese medicine compounds regulate autophagy for treating neurodegenerative disease: A mechanism review” [ Biomed. Pharamacother. 133, (2021) 110968]
Degradation of lipid droplets by chimeric autophagy-tethering compounds
Qingyangshen mitigates amyloid-β and Tau aggregate defects involving PPARα-TFEB activation in transgenic mice of Alzheimer's disease
TFEB, a master regulator of autophagy and biogenesis, unexpectedly promotes apoptosis in response to the cyclopentenone prostaglandin 15d-PGJ2
Pharmacological enhancement of TFEB-mediated autophagy alleviated neuronal death in oxidative stress-induced Parkinson’s disease models
Traditional Chinese medicine compounds regulate autophagy for treating neurodegenerative disease: A mechanism review
Transcription factor EB: an emerging drug target for neurodegenerative disorders
Targeting Aggrephagy for the Treatment of Alzheimer’s Disease
A Curcumin Derivative Activates TFEB and Protects Against Parkinsonian Neurotoxicity in Vitro
Personalized Body Constitution Inquiry Based on Machine Learning
Allele-selective lowering of mutant HTT protein by HTT–LC3 linker compounds
Balancing mTOR Signaling and Autophagy in the Treatment of Parkinson’s Disease
NeuroDefend, a novel Chinese medicine, attenuates amyloid-β and tau pathology in experimental Alzheimer's disease models