Area of research
Sensory Systems · Molecular Biology
Research interest
Research interests include Hearing, Cochlea, Tinnitus, Genetics, Cardiovascular Function and Risk Factors, Advanced biosensing and bioanalysis techniques, and Ion channel regulation and function.
Combined AAV-mediated specific Gjb2 expression restores hearing in DFNB1 mouse models
AAV-Sparcl1 promotes hair cell regeneration by increasing supporting cell plasticity
Establishment of a Cochlear Organoid Platform for Remodeling the Extracellular Matrix
Optimized in vivo base editing restores auditory function in a DFNA15 mouse model
AAV‐Mediated Gene Therapy Restores Hearing in Patients with DFNB9 Deafness
AAV‐mediated Gene Cocktails Enhance Supporting Cell Reprogramming and Hair Cell Regeneration
Modeling, applications and challenges of inner ear organoid
<scp>AAV</scp>‐mediated <i>Gpm6b</i> expression supports hair cell reprogramming
Molecular insights into the activation mechanism of GPR156 in maintaining auditory function
<i>Pcolce2</i> overexpression promotes supporting cell reprogramming in the neonatal mouse cochlea
AAV-regulated Serpine2 overexpression promotes hair cell regeneration
Clinical practice guidelines for gene therapy to treat hereditary hearing loss
Aldose reductase inhibition alleviates diabetic cardiomyopathy and is associated with a decrease in myocardial fatty acid oxidation
AAV-Net1 facilitates the trans-differentiation of supporting cells into hair cells in the murine cochlea
<scp><i>Rps14</i></scp> upregulation promotes inner ear progenitor proliferation and hair cell regeneration in the neonatal mouse cochlea
Critical role of TPRN rings in the stereocilia for hearing
The role of Espin in the stereocilia regeneration and protection in Atoh1‐overexpressed cochlear epithelium
Rassf2 overexpression mediated by AAV promotes the supporting cell-to-hair cell transformation in the cochlea
Promotion of angiogenesis in vitro by Astragalus polysaccharide via activation of TLR4 signaling pathway
Absence of Serpinb6a causes progressive hair cell apoptosis and hearing loss in mice
Disruption of the autism-related gene Pak1 causes stereocilia disorganization, hair cell loss, and deafness in mice
Circular RNA-HIPK3 regulates human pulmonary artery endothelial cells function and vessel growth by regulating microRNA-328-3p/STAT3 axis.
Follow-up Care for Patients Receiving Immune Checkpoint Inhibitors
Blebbistatin Inhibits Neomycin-Induced Apoptosis in Hair Cell-Like HEI-OC-1 Cells and in Cochlear Hair Cells
Espin distribution as revealed by super-resolution microscopy of stereocilia.
PubMed 2020cited by 50position: middle
Knockdown of Foxg1 in supporting cells increases the trans-differentiation of supporting cells into hair cells in the neonatal mouse cochlea
Postnatal delayed growth impacts cognition but rescues programmed impaired pulmonary vascular development in an IUGR rat model
Dendrobine targeting JNK stress signaling to sensitize chemotoxicity of cisplatin against non-small cell lung cancer cells in vitro and in vivo
Preparation and evaluation of lipid polymer nanoparticles for eradicating H. pylori biofilm and impairing antibacterial resistance in vitro
High Prevalence of Fluoroquinolone-Resistant Group B Streptococci among Clinical Isolates in China and Predominance of Sequence Type 19 with Serotype III