Area of research
Molecular Biology · Cancer Research
Research interest
Research interests include Cancer, Hypoxia, and Metabolism, Epigenetics and DNA Methylation, RNA modifications and cancer, and Mitochondrial Function and Pathology.
The microbial metabolite I3A inhibits ferroptosis and the effectiveness of redox-based cancer therapy.
KRAS<sup>G12D</sup> mutation promotes pancreatic tumorigenesis by suppressing sirtuin three via the guanine nucleotide exchange factor RCC1.
Mitochondrial metabolism as a pharmacological target for cancer therapeutics
Cardiomyocyte-localized CCDC25 senses NET DNA to promote doxorubicin cardiotoxicity by activating autophagic flux
Tryptophan Metabolite Indole‐3‐Aldehyde Induces AhR and c‐MYC Degradation to Promote Tumor Immunogenicity
Tryptophan Metabolite Indole-3-Aldehyde Induces AhR and c-MYC Degradation to Promote Tumor Immunogenicity.
Cardiomyocyte-localized CCDC25 senses NET DNA to promote doxorubicin cardiotoxicity by activating autophagic flux.
SQLE-catalyzed squalene metabolism promotes mitochondrial biogenesis and tumor development in K-ras-driven cancer.
Targeting oncogenic activation of FLT3/SREBP/FASN promotes the therapeutic effect of quizartinib involving disruption of mitochondrial phospholipids.
Targeting ROS in cancer: rationale and strategies
Targeting ROS in cancer: rationale and strategies.
An end-to-end deep learning method for mass spectrometry data analysis to reveal disease-specific metabolic profiles
An end-to-end deep learning method for mass spectrometry data analysis to reveal disease-specific metabolic profiles.
Wild-type IDH2 is a therapeutic target for triple-negative breast cancer
Squalene-epoxidase-catalyzed 24(S),25-epoxycholesterol synthesis promotes trained-immunity-mediated antitumor activity
High expression of PPP1CC promotes NHEJ-mediated DNA repair leading to radioresistance and poor prognosis in nasopharyngeal carcinoma
The Association Between Tumor Radiomic Analysis and Peritumor Habitat‐Derived Radiomic Analysis on Gadoxetate Disodium‐Enhanced <scp>MRI</scp> With Microvascular Invasion in Hepatocellular Carcinoma
Scutellarin: pharmacological effects and therapeutic mechanisms in chronic diseases
Wild-type IDH2 is a therapeutic target for triple-negative breast cancer.
Cancer cell-intrinsic biosynthesis of itaconate promotes tumor immunogenicity
High expression of PPP1CC promotes NHEJ-mediated DNA repair leading to radioresistance and poor prognosis in nasopharyngeal carcinoma.
The rheumatoid arthritis drug auranofin exerts potent anti-lymphoma effect by stimulating TXNRD-mediated ROS generation and inhibition of energy metabolism
Extraction, purification, structural characterization, and bioactivities of Ginkgo biloba leave polysaccharides: A review
Cancer cell-intrinsic biosynthesis of itaconate promotes tumor immunogenicity.
HKDC1 functions as a glucose sensor and promotes metabolic adaptation and cancer growth via interaction with PHB2.
The rheumatoid arthritis drug auranofin exerts potent anti-lymphoma effect by stimulating TXNRD-mediated ROS generation and inhibition of energy metabolism.
Global miRNA profiling reveals key molecules that contribute to different chronic lymphocytic leukemia incidences in Asian and Western populations.
Nardilysin-regulated scission mechanism activates polo-like kinase 3 to suppress the development of pancreatic cancer.
SQLE-mediated squalene metabolism promotes tumor immune evasion in pancreatic cancer.
SQLE-mediated squalene metabolism is critical for mitochondrial biogenesis and tumor development in K-ras-driven cancer
FMitF: Track I: Synthesizing Semantic Checkers for Runtime Verification of Production Distributed Systems
CNS Core: Small: Intelligent Fault Injection to Expose and Reproduce Production-Grade Bugs in Cloud Systems
CAREER: Towards Gray-Fault Tolerant Cloud through Harnessing and Enhancing System Observability
CNS Core: Small: Intelligent Fault Injection to Expose and Reproduce Production-Grade Bugs in Cloud Systems
CAREER: Towards Gray-Fault Tolerant Cloud through Harnessing and Enhancing System Observability
CRII: CSR: Toward Understanding and Automatically Detecting Specious Configuration in Large Systems