Area of research
Surgery · Hepatology
Research interest
Research interests include Cholangiocarcinoma and Gallbladder Cancer Studies, Hepatocellular Carcinoma Treatment and Prognosis, Cancer Immunotherapy and Biomarkers, and RNA modifications and cancer.
Stromal architecture and fibroblast subpopulations with opposing effects on outcomes in hepatocellular carcinoma
Metabolism archetype cancer cells induce protumor TREM2+ macrophages via oxLDL-mediated metabolic interplay in hepatocellular carcinoma
Targeting SRSF1 improves cancer immunotherapy by dually acting on CD8+T and tumor cells
Conversion therapy of tislelizumab plus lenvatinib and GEMOX in unresectable locally advanced biliary tract cancer (ZSAB-TransGOLP): a multicentre, prospective, phase 2 study
Adjuvant camrelizumab combined with capecitabine in patients with intrahepatic cholangiocarcinoma after surgical resection in China (ACC): a single-arm, single-centre, open-label, phase 2 trial
Contemporaneous and temporal symptom drivers during breast cancer chemotherapy: A prospective repeated-measures cohort study
Targeting tumor-intrinsic BCL9 reverses immunotherapy resistance by eliciting macrophage-mediated phagocytosis and antigen presentation
CD177 <sup>+</sup> neutrophils drive extracellular matrix remodelling and HGF-alpha release in ALPPS-induced liver regeneration
FAITH trial: Feasibility and safety of anlotinib plus benmelstobart in patients with previously immunotherapy treated intermediate-to-advanced hepatocellular carcinoma—Amulticenter, single arm, prospective phase Ⅱ trial.
Demoralization and dignity loss in breast cancer: A network analysis and computer simulation study
Neutrophil profiling illuminates anti-tumor antigen-presenting potency
A blueprint for tumor-infiltrating B cells across human cancers
CRKL dictates anti-PD-1 resistance by mediating tumor-associated neutrophil infiltration in hepatocellular carcinoma
Macro CD5L+ deteriorates CD8+T cells exhaustion and impairs combination of Gemcitabine-Oxaliplatin-Lenvatinib-anti-PD1 therapy in intrahepatic cholangiocarcinoma
Cancer-associated fibroblasts contributed to hepatocellular carcinoma recurrence and metastasis via CD36-mediated fatty-acid metabolic reprogramming
Targeting GSDME-mediated macrophage polarization for enhanced antitumor immunity in hepatocellular carcinoma
ACE2 Enhances Sensitivity to PD-L1 Blockade by Inhibiting Macrophage-Induced Immunosuppression and Angiogenesis
RECQL4 Inhibits Radiation‐Induced Tumor Immune Awakening via Suppressing the cGAS‐STING Pathway in Hepatocellular Carcinoma
Inhibition of SIRT1 relieves hepatocarcinogenesis via alleviating autophagy and inflammation
Characterization of tumor microbiome and associations with prognosis in intrahepatic cholangiocarcinoma
A <scp>Transformer‐Based</scp> microvascular invasion classifier enhances prognostic stratification in <scp>HCC</scp> following radiofrequency ablation
Prolonged Survival of Neutrophils Induced by Tumor‐Derived G‐CSF/GM‐CSF Promotes Immunosuppression and Progression in Laryngeal Squamous Cell Carcinoma
Whole-exome sequencing reveals genomic landscape of intrahepatic cholangiocarcinoma and identifies SAV1 as a potential driver
CYLD induces high oxidative stress and DNA damage through class I HDACs to promote radiosensitivity in nasopharyngeal carcinoma
Distinct immune microenvironment of venous tumor thrombus in hepatocellular carcinoma at single-cell resolution
Lactylome analysis suggests lactylation-dependent mechanisms of metabolic adaptation in hepatocellular carcinoma
Atezolizumab plus bevacizumab versus active surveillance in patients with resected or ablated high-risk hepatocellular carcinoma (IMbrave050): a randomised, open-label, multicentre, phase 3 trial
CD36+ cancer-associated fibroblasts provide immunosuppressive microenvironment for hepatocellular carcinoma via secretion of macrophage migration inhibitory factor
An invasive zone in human liver cancer identified by Stereo-seq promotes hepatocyte–tumor cell crosstalk, local immunosuppression and tumor progression
A review of 2022 Chinese clinical guidelines on the management of hepatocellular carcinoma: updates and insights
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