Xuhui Liu

Blood Flow Restriction Therapy Stimulates Intercellular Mitochondria Transfer and Improves Muscle Regeneration and Shoulder Function in a Murine Rotator Cuff Injury Model.

Fibrotic differentiation profile of skeletal and cardiac muscle fibroadipogenic progenitors in D2-mdx mouse.

Spatial transcriptomics reveals macrophage domestication by epithelial cells promotes immunotherapy resistance in small cell lung cancer

The relationship between vitamin D levels and Alzheimer’s disease risk: insights from a centenarian study of Chinese women

Overuse-Induced Muscle Disorder: Establishing a Rat Model to Unravel the Role of Fibro-Adipogenic Progenitor Cells in Intramuscular Fibrosis.

Wang KC, Lau J, Garcia SM, Wague A, Sharma S, Liu X, Feeley BT. The influence of age on cellular senescence in injured versus healthy muscle and its implications on rotator cuff injuries. J Shoulder Elbow Surg. 2025 Jun; 34(6S):S117-S126. PMID: 40057173

Pfaff MR, Wague A, Davies M, Killaars AR, Ning D, Garcia S, Nguyen A, Nuthalapati P, Liu M, Liu X, Feeley BT, Healy KE. Viscoelastic HyA Hydrogel Promotes Recovery of Muscle Quality and Vascularization in a Murine Model of Delayed Rotator Cuff Repair. Adv Healthc Mater. 2025 Apr; 14(10):e2403962. PM

Defining Endogenous Mitochondrial Transfer in Muscle After Rotator Cuff Injury

Age-dependent decline of B3AR agonist-mediated activation of FAP UCP-1 expression in murine models of chronic rotator cuff repair.

Zhang H, Wague A, Diaz A, Liu M, Sang L, Youn A, Sharma S, Milan N, Kim H, Feeley B, Liu X. Overexpression of PRDM16 improves muscle function after rotator cuff tears. J Shoulder Elbow Surg. 2024 Dec; 33(12):2725-2733. PMID: 39032686

Diaz A, Sang L, Garcia S, Wague A, Davies M, Youn A, Liu X, Feeley BT. Age-dependent decline of B3AR agonist-mediated activation of FAP UCP-1 expression in murine models of chronic rotator cuff repair. J Orthop Res. 2024 Oct; 42(10):2307-2317. PMID: 38796742

Garcia SM, Lau J, Diaz A, Chi H, Lizarraga M, Wague A, Montenegro C, Davies MR, Liu X, Feeley BT. Distinct human stem cell subpopulations drive adipogenesis and fibrosis in musculoskeletal injury. bioRxiv. 2024 Jan 05. PMID: 38260367

Chi HM, Davies MR, Garcia SM, Montenegro C, Sharma S, Lizarraga M, Wang Z, Nuthalapati P, Kim HT, Liu X, Feeley BT. Defining Endogenous Mitochondrial Transfer in Muscle After Rotator Cuff Injury. Am J Sports Med. 2024 02; 52(2):451-460. PMID: 38174367

Polarized macrophages regulate fibro/adipogenic progenitor (FAP) adipogenesis through exosomes

Polarized macrophages regulate fibro/adipogenic progenitor (FAP) adipogenesis through exosomes.

Darevsky DM, Hu DA, Gomez FA, Davies MR, Liu X, Feeley BT. Algorithmic assessment of shoulder function using smartphone video capture and machine learning. Sci Rep. 2023 11 15; 13(1):19986. PMID: 37968288

Liu M, Ng M, Phu T, Bouchareychas L, Feeley BT, Kim HT, Raffai RL, Liu X. Polarized macrophages regulate fibro/adipogenic progenitor (FAP) adipogenesis through exosomes. Stem Cell Res Ther. 2023 11 07; 14(1):321. PMID: 37936229

Darevsky DM, Hu DA, Gomez FA, Davies MR, Liu X, Feeley BT. A Tool for Low-Cost, Quantitative Assessment of Shoulder Function Using Machine Learning. medRxiv. 2023 Apr 17. PMID: 37131827

A novel mouse model of hindlimb joint contracture with 3D-printed casts.

Microenergy acoustic pulses promotes muscle regeneration through in situ activation of muscle stem cells.

Liu M, Feeley BT, Kim HT, Liu X. The Role of Matrix Metalloproteinase-13 (MMP13) in TGFβ/BMP Pathway Regulation of Fibro-Adipogenic Progenitor (FAP) Differentiation. Cell Physiol Biochem. 2022 Dec 20; 56(6):730-743. PMID: 36537139

Davies MR, Garcia S, Liu M, Chi H, Kim HT, Raffai RL, Liu X, Feeley BT. Muscle-Derived Beige Adipose Precursors Secrete Promyogenic Exosomes That Treat Rotator Cuff Muscle Degeneration in Mice and Are Identified in Humans by Single-Cell RNA Sequencing. Am J Sports Med. 2022 07; 50(8):2247-2257. PMID

Moore LK, Lee CS, Agha O, Liu M, Zhang H, Dang ABC, Dang A, Liu X, Feeley BT. A novel mouse model of hindlimb joint contracture with 3D-printed casts. J Orthop Res. 2022 12; 40(12):2865-2872. PMID: 35266583

Davies MR, Chi H, Kaur G, Liu M, Ma CB, Kim HT, Liu X, Feeley BT. Rotator Cuff Tear Size Regulates Fibroadipogenic Progenitor Number and Gene Expression Profile in the Supraspinatus Independent of Patient Age. Am J Sports Med. 2022 01; 50(1):208-215. PMID: 34779676

Zhang H, Kim HT, Feeley BT, Lin G, Lue TF, Liu M, Banie L, Liu X. Microenergy acoustic pulses promotes muscle regeneration through in situ activation of muscle stem cells. J Orthop Res. 2022 07; 40(7):1621-1631. PMID: 34657315

Trichostatin A regulates fibro/adipogenic progenitor adipogenesis epigenetically and reduces rotator cuff muscle fatty infiltration.

Preconditioning improves muscle regeneration after ischemia-reperfusion injury.

J.H. Jay, M. Liu, X. Liu, B.T. Feeley, C.S. Sabatini. Does the Antimalarial Drug Quinine Contribute to Muscle Fibro/Adipogenic Progenitor Fibrogenesis?. Muscles Ligaments and Tendons Journal. 2021 Nov 1; 11(04):635.

G. Kaur, M.R. Davies, X. Liu, B.T. Delioglu. The Role of Fibro-Adipogenic Progenitors in Musculoskeletal Disease. Muscles Ligaments and Tendons Journal. 2021 May 1; 11(02):201.

Davies MR, Kaur G, Liu X, Alvarado FG, Nuthalapati P, Liu M, Diaz A, Lotz JC, Bailey JF, Feeley BT. Paraspinal muscle degeneration and regenerative potential in a Murine model of Lumbar Disc Injury. N Am Spine Soc J. 2021 Jun; 6:100061. PMID: 35141626