Area of research
Epidemiology · Pathology and Forensic Medicine
Research interest
Research focused on Endocrinology and Lipotoxicity, with related work in Fatty liver, AMPK, Autophagy. Notable publications include 'BMI is Strongly Associated With Hypertension, and Waist Circumference is Strongly Associated With Type 2 Diabetes and Dyslipidemia, in Northern Chinese Adults', 'Therapeutic Role of Ursolic Acid on Ameliorating Hepatic Steatosis and Improving Metabolic Disorders in High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease Rats', and 'Prenatal exposure to famine and the development of hyperglycemia and type 2 diabetes in adulthood across consecutive generations: a population-based cohort study of families in...'.
Hepatic NMNAT1 is required to defend against alcohol-associated fatty liver disease
Magnetic UiO-66-NO<sub>2</sub> Nanocomposite for Highly Efficient Adsorption and Detection of Sugar Phosphates in Biological Samples
The roles of polysaccharides in rheumatoid arthritis treatment: A review focusing on the sources, structures and their related mechanism
mTORC1 inhibition uncouples lipolysis and thermogenesis in white adipose tissue to contribute to alcoholic liver disease
Integrating network pharmacology and experimental verification strategies to reveal the active ingredients and molecular mechanism of Tenghuang Jiangu Capsule against osteoporosis
Integrating Network Pharmacology and Experimental Verification Strategies to Reveal the Active Ingredients and Molecular Mechanism of Tenghuang Jiangu Capsule Against Osteoporosis
Extracellular vesicles secreted from mesenchymal stem cells exert anti-apoptotic and anti-inflammatory effects via transmitting microRNA-18b in rats with diabetic retinopathy
Prevalences of metabolic syndrome and its sex-specific association with socioeconomic status in rural China: a cross-sectional study
A Network Pharmacology and Molecular Docking Strategy to Explore Potential Targets and Mechanisms Underlying the Effect of Curcumin on Osteonecrosis of the Femoral Head in Systemic Lupus Erythematosus
Activation of AMP-Activated Protein Kinase-Sirtuin 1 Pathway Contributes to Salvianolic Acid A-Induced Browning of White Adipose Tissue in High-Fat Diet Fed Male Mice
Glutathione disulfide sensitizes hepatocytes to TNFα-mediated cytotoxicity via IKK-β S-glutathionylation: a potential mechanism underlying non-alcoholic fatty liver disease
The <scp>TLR</scp>4‐<scp>IRE</scp>1α pathway activation contributes to palmitate‐elicited lipotoxicity in hepatocytes
Sirtuin 3 acts as a negative regulator of autophagy dictating hepatocyte susceptibility to lipotoxicity
Nicotinamide protects hepatocytes against palmitate-induced lipotoxicity via SIRT1-dependent autophagy induction
MicroRNA-1185 Induces Endothelial Cell Apoptosis by Targeting UVRAG and KRIT1
Increasing extracellular Ca2+ sensitizes TNF-alpha-induced vascular cell adhesion molecule-1 (VCAM-1) via a TRPC1/ERK1/2/NFκB-dependent pathway in human vascular endothelial cells
Histidine-alleviated hepatocellular death in response to 4-hydroxynonenal contributes to the protection against high-fat diet-induced liver injury
Prenatal exposure to famine and the development of hyperglycemia and type 2 diabetes in adulthood across consecutive generations: a population-based cohort study of families in Suihua, China
Elevated circulating stearic acid leads to a major lipotoxic effect on mouse pancreatic beta cells in hyperlipidaemia via a miR-34a-5p-mediated PERK/p53-dependent pathway
Serum metabonomics of NAFLD plus T2DM based on liquid chromatography–mass spectrometry
Insulin Protects Hepatic Lipotoxicity by Regulating ER Stress through the PI3K/Akt/p53 Involved Pathway Independently of Autophagy Inhibition
Increase of circulating cholesterol in vitamin D deficiency is linked to reduced vitamin D receptor activity via the Insig‐2/SREBP‐2 pathway
Ursolic acid increases energy expenditure through enhancing free fatty acid uptake and β‐oxidation via an UCP3/AMPK‐dependent pathway in skeletal muscle
Nicotinamide ameliorates palmitate-induced ER stress in hepatocytes via cAMP/PKA/CREB pathway-dependent Sirt1 upregulation
Ursolic acid protects hepatocytes against lipotoxicity through activating autophagy via an AMPK pathway
Therapeutic Role of Ursolic Acid on Ameliorating Hepatic Steatosis and Improving Metabolic Disorders in High-Fat Diet-Induced Non-Alcoholic Fatty Liver Disease Rats
Histidine supplementation alleviates inflammation in the adipose tissue of high-fat diet-induced obese rats via the NF-κB- and PPARγ-involved pathways
Rectification of impaired adipose tissue methylation status and lipolytic response contributes to hepatoprotective effect of betaine in a mouse model of alcoholic liver disease
Biomarkers Identified by Urinary Metabonomics for Noninvasive Diagnosis of Nutritional Rickets