Chang‐Woo Lee

Pellino1-mTOR/S6K1 signaling axis is a key pathogenesis for the development of polycystic kidney disease.

Protective Effect of Brain Derived Neurotrophic Factor-Overexpressing Wharton's Jelly-Derived Mesenchymal Stromal Cells in Severe Intraventricular Hemorrhage in Newborn Rats.

The ubiquitin ligase Pellino1 targets STAT3 to regulate macrophage-mediated inflammation and tumor development.

Soluble receptors in cancer: mechanisms, clinical significance, and therapeutic strategies.

Longitudinal single-cell transcriptional dynamics throughout neurodegeneration in SCA1

Ssu72 phosphatase is essential for thermogenic adaptation by regulating cytosolic translation.

Phosphatase Ssu72 Is Essential for Homeostatic Balance Between CD4⁺ T Cell Lineages.

The Pellino1-PKCθ Signaling Axis Is an Essential Target for Improving Antitumor CD8+ T-lymphocyte Function.

Protein phosphatases regulate the liver microenvironment in the development of hepatocellular carcinoma.

Ssu72-HNF4α signaling axis classify the transition from steatohepatitis to hepatocellular carcinoma.

Mammalian Ssu72 phosphatase preferentially considers tissue-specific actively transcribed gene expression by regulating RNA Pol II transcription.

Ssu72 is a T-cell receptor-responsive modifier that is indispensable for regulatory T cells.

Ssu72 phosphatase directly binds to ZAP-70, thereby providing fine-tuning of TCR signaling and preventing spontaneous inflammation.

Dysregulation of cancer genes by recurrent intergenic fusions

Pellino1 regulates reversible ATM activation via NBS1 ubiquitination at DNA double-strand breaks.

De novo phosphorylation of H2AX by WSTF regulates transcription-coupled homologous recombination repair.

Senataxin mutations elicit motor neuron degeneration phenotypes and yield TDP-43 mislocalization in ALS4 mice and human patients