Area of research
Cancer Research · Oncology
Research interest
Research interests include Cancer Genomics and Diagnostics, Cancer Cells and Metastasis, Genetic factors in colorectal cancer, and Acute Myeloid Leukemia Research.
Delineation of the heterogeneity underlying genomic instability in hereditary breast cancers reveals four disease subtypes.
Explainable Machine Learning for Assessing Digital Health Literacy in Older Adults: Validation and Development of a Two-Stage Model Integrating Performance-Based and Self-Assessed Indicators.
Spatial dissection of tumour microenvironments in gastric cancers reveals the immunosuppressive crosstalk between <i>CCL2+</i> fibroblasts and <i>STAT3</i>-activated macrophages.
Tafasitamab, lenalidomide, and rituximab in relapsed or refractory follicular lymphoma (inMIND): a global, phase 3, randomised controlled trial
Explainable Machine Learning for Assessing Digital Health Literacy in Older Adults: Validation and Development of a Two-Stage Model Integrating Performance-Based and Self-Assessed Indicators (Preprint)
Evolutionary dependency of cancer mutations in gene pairs inferred by nonsynonymous-synonymous mutation ratios.
High-resolution genomic configuration of <i>FGFR</i> rearrangements dictates the therapeutic vulnerability of squamous cell lung cancers.
A Subset of Microsatellite Unstable Cancer Genomes Prone to Short Insertions over Deletions Is Associated with Elevated Anticancer Immunity.
Cellular abundance-based prognostic model associated with deregulated gene expression of leukemic stem cells in acute myeloid leukemia.
<i>Fusobacterium nucleatum</i> induces a tumor microenvironment with diminished adaptive immunity against colorectal cancers.
Whole-Genome Sequencing Reveals Mutational Signatures Related to Radiation-Induced Sarcomas and DNA-Damage-Repair Pathways.
Longitudinal Transcription Profiling of Bladder Cancers Dictate the Response to BCG Treatment and Disease Progression.
Longitudinal Analyses of Mutational Subclonal Architecture and Tumor Subtypes in Recurrent Bladder Cancer.
The shaping of cancer genomes with the regional impact of mutation processes.
Transcriptional Profiling Reveals Mesenchymal Subtypes of Small Cell Lung Cancer with Activation of the Epithelial-to-Mesenchymal Transition and Worse Clinical Outcomes.
Spatially Distinct Reprogramming of the Tumor Microenvironment Based On Tumor Invasion in Diffuse-Type Gastric Cancers.
Human kidney organoids reveal the role of glutathione in Fabry disease.
Correlation-based and feature-driven mutation signature analyses to identify genetic features associated with DNA mutagenic processes in cancer genomes.
Cross-species oncogenic signatures of breast cancer in canine mammary tumors.
Mouse-human co-clinical trials demonstrate superior anti-tumour effects of buparlisib (BKM120) and cetuximab combination in squamous cell carcinoma of head and neck.
Phase 2 study of afatinib among patients with recurrent and/or metastatic esophageal squamous cell carcinoma.
Gene expression signatures associated with sensitivity to azacitidine in myelodysplastic syndromes.
Genomic, transcriptomic, and viral integration profiles associated with recurrent/metastatic progression in high-risk human papillomavirus cervical carcinomas.
Distinct mutation profiles between primary bladder cancer and circulating tumor cells warrant the use of circulating tumors cells as cellular resource for mutation follow-up.
Mutation Analysis of Colorectal and Gastric Carcinomas Originating from Adenomas: Insights into Genomic Evolution Associated with Malignant Progression.
Mutation heterogeneity between primary gastric cancers and their matched lymph node metastases.
Identification of Local Clusters of Mutation Hotspots in Cancer-Related Genes and Their Biological Relevance.
Impact of in vitro driven expression signatures of CD133 stem cell marker and tumor stroma on clinical outcomes in gastric cancers.
A molecular portrait of microsatellite instability across multiple cancers
Injury-Mediated Vascular Regeneration Requires Endothelial ER71/ETV2